The clonal and mutational evolution spectrum of primary triple-negative breast cancers

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

Primary triple-negative breast cancers (TNBCs), a tumour type defined by lack of oestrogen receptor, progesterone receptor and ERBB2 gene amplification, represent approximately 16% of all breast cancers. Here we show in 104 TNBC cases that at the time of diagnosis these cancers exhibit a wide and co...

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Bibliographic Details
Main Authors: Shah, S., Roth, A., Goya, R., Oloumi, A., Ha, G., Zhao, Y., Turashvili, G., Ding, J., Tse, K., Haffari, G., Bashashati, A., Prentice, L., Khattra, J., Burleigh, A., Yap, D., Bernard, V., McPherson, A., Shumansky, K., Crisan, A., Giuliany, R., Heravi-Moussavi, A., Rosner, J., Lai, D., Birol, I., Varhol, Richard, Tam, A., Dhalla, N., Zeng, T., Ma, K., Chan, S., Griffith, M., Moradian, A., Cheng, S., Morin, G., Watson, P., Gelmon, K., Chia, S., Chin, S., Curtis, C., Rueda, O., Pharoah, P., Damaraju, S., MacKey, J., Hoon, K., Harkins, T., Tadigotla, V., Sigaroudinia, M., Gascard, P., Tlsty, T., Costello, J., Meyer, I., Eaves, C., Wasserman, W., Jones, S., Huntsman, D., Hirst, M., Caldas, C., Marra, M., Aparicio, S.
Format: Journal Article
Published: 2012
Online Access:http://hdl.handle.net/20.500.11937/36670

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