New insight into the intracellular roles of class II phosphoinositide 3-kinases

QR Code

New insight into the intracellular roles of class II phosphoinositide 3-kinases

In the last few years, an increased attention to class II isoforms of phosphoinositide 3-kinase (PI3K) has emerged, mainly fuelled by evidence suggesting a distinct non-redundant role for these enzymes compared with other PI3Ks. Despite this renewed interest, many questions remain on the specific fu...

Full description

Bibliographic Details
Main Authors:	Maffucci, T., Falasca, Marco
Format:	Journal Article
Published:	Portland Press 2014
Online Access:	http://hdl.handle.net/20.500.11937/36636

Similar Items

Regulation and cellular functions of class II phosphoinositide 3-kinases
by: Falasca, Marco, et al.
Published: (2012)

Class II Phosphoinositide 3-Kinases Contribute to Endothelial Cells Morphogenesis
by: Tibolla, G., et al.
Published: (2013)

Key role of phosphoinositide 3-kinase class IB in pancreatic cancer
by: Edling, C., et al.
Published: (2010)

Class II Phosphoinositide 3-Kinases as Novel Drug Targets
by: Falasca, Marco, et al.
Published: (2017)

Novel roles for class II Phosphoinositide 3-Kinase C2ß in signalling pathways involved in prostate cancer cell invasion.
by: Mavrommati, I., et al.
Published: (2016)

Analysis, regulation, and roles of endosomal phosphoinositides
by: Maffucci, T., et al.
Published: (2014)

Investigating the mechanisms of activation and action of phosphoinositide 3-kinase C2 alpha in pancreatic beta cells
by: Mazza, S., et al.
Published: (2013)

Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic ß cells
by: Dominguez, V., et al.
Published: (2011)

Phosphoinositide 3-kinase pathway inhibitors: pharmacology, metabolism & drug development
by: Falasca, Marco
Published: (2011)

Genetic and epigenetic regulation of phosphoinositide 3-kinase isoforms
by: Fyffe, C., et al.
Published: (2013)

THE CLASS II PHOSPHOINOSITIDE 3-KINASE ISOFORM beta REGULATES PLATELET FUNCTION AND ARTERIAL THROMBOSIS IN MICE
by: Tibolla, G., et al.
Published: (2011)

Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway
by: Edling, C., et al.
Published: (2014)

3-phosphoinositide-dependent protein kinase-1 as an emerging target in the management of breast cancer
by: Fyffe, C., et al.
Published: (2013)

Class II phosphoinositide 3-kinase C2ß regulates a novel signaling pathway involved in breast cancer progression.
by: Chikh, A., et al.
Published: (2016)

A phosphoinositide 3-kinase/phospholipase cgamma1 pathway regulates fibroblast growth factor-induced capillary tube formation
by: Maffucci, T., et al.
Published: (2009)

Targeting phosphoinositide 3-kinase pathways in pancreatic cancer - from molecular signalling to clinical trials
by: Falasca, Marco, et al.
Published: (2011)

Phosphoinositides signalling in cancer: Focus on PI3K and PLC
by: Raimondi, C., et al.
Published: (2012)

Elucidation of the WNT & AKT/Phosphoinositide-3-Kinase Pathways in Colorectal Carcinoma
by: Khor, Tin Oo
Published: (2004)

Rethinking phosphatidylinositol 3-monophosphate
by: Falasca, Marco, et al.
Published: (2009)

Functional association of phosphoinositide-3-kinase with platelet glycoprotein Iba, the major ligand-binding subunit of the glycoprotein Ib-IX-V complex
by: Mu, F., et al.
Published: (2010)

Cudraflavone C induces tumor-specific apoptosis in colorectal cancer cells through inhibition of the phosphoinositide 3-kinase (PI3K)-AKT pathway
by: Castresana, Javier S., et al.
Published: (2017)

Targeting p110gamma in gastrointestinal cancers: attack on multiple fronts
by: Falasca, Marco, et al.
Published: (2014)

Akt/protein kinase B in skeletal muscle physiology and pathology
by: Wu, M., et al.
Published: (2011)

Increases in intracellular calcium perturb blood–brain barrier via protein kinase C-alpha and apoptosis
by: Rakkar, Kamini, et al.
Published: (2016)

The role of the focal adhesion kinase Pyk2 in platelet activation
by: Cipolla, L., et al.
Published: (2011)

The role of the focal adhesion kinase PYK2 in platelet activation
by: Canobbio, I., et al.
Published: (2011)

Role and regulation of phosphatidylinositol 3-kinase ß in platelet integrin α2ß1 signaling
by: Consonni, A., et al.
Published: (2012)

Molecular targets of colorectal cancer: an insight on intracellular cellular signaling pathways
by: Pandurangan, Ashok Kumar, et al.
Published: (2014)

Development of optical pH nanosensors for biological insights into the intracellular trafficking of nanomedicines
by: Desai, Arpan
Published: (2014)

Cancer chemoprevention with nuts.
by: Falasca, Marco, et al.
Published: (2014)

The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation
by: Pieiro, R., et al.
Published: (2011)

Boyden chamber
by: Falasca, Marco, et al.
Published: (2011)

PITPs as targets for selectively interfering with phosphoinositide signaling in cells
by: Nile, A., et al.
Published: (2014)

Activation of phosphatidylinositol 3-kinase ß by the platelet collagen receptors integrin a2ß1 and GPVI: The role of Pyk2 and c-Cbl
by: Manganaro, D., et al.
Published: (2015)

The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets
by: Canobbio, I., et al.
Published: (2015)

The proline-rich tyrosine kinase Pyk2 regulates platelet integrin aIIbß3 outside-in signaling
by: Cipolla, L., et al.
Published: (2013)

PI3K Class II [alpha] Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function
by: Franco, I., et al.
Published: (2014)

Intracellular delivery of therapeutic antibodies
by: Hackett, Gavin S.
Published: (2012)

Modelling of intracellular calcium dynamics
by: Tilūnaitė, Agnė
Published: (2018)

LIM kinase function and renal growth: potential role for LIM kinases in fetal programming of kidney development
by: Sparrow, Alexander J., et al.
Published: (2017)