New insight into the intracellular roles of class II phosphoinositide 3-kinases
In the last few years, an increased attention to class II isoforms of phosphoinositide 3-kinase (PI3K) has emerged, mainly fuelled by evidence suggesting a distinct non-redundant role for these enzymes compared with other PI3Ks. Despite this renewed interest, many questions remain on the specific fu...
| Main Authors: | , |
|---|---|
| Format: | Journal Article |
| Published: |
Portland Press
2014
|
| Online Access: | http://hdl.handle.net/20.500.11937/36636 |
| _version_ | 1848754825883287552 |
|---|---|
| author | Maffucci, T. Falasca, Marco |
| author_facet | Maffucci, T. Falasca, Marco |
| author_sort | Maffucci, T. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | In the last few years, an increased attention to class II isoforms of phosphoinositide 3-kinase (PI3K) has emerged, mainly fuelled by evidence suggesting a distinct non-redundant role for these enzymes compared with other PI3Ks. Despite this renewed interest, many questions remain on the specific functions regulated by these isoforms and their mechanism of activation and action. In the present review, we discuss results from recent studies that have provided some answers to these questions. |
| first_indexed | 2025-11-14T08:46:34Z |
| format | Journal Article |
| id | curtin-20.500.11937-36636 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:46:34Z |
| publishDate | 2014 |
| publisher | Portland Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-366362017-09-13T15:28:50Z New insight into the intracellular roles of class II phosphoinositide 3-kinases Maffucci, T. Falasca, Marco In the last few years, an increased attention to class II isoforms of phosphoinositide 3-kinase (PI3K) has emerged, mainly fuelled by evidence suggesting a distinct non-redundant role for these enzymes compared with other PI3Ks. Despite this renewed interest, many questions remain on the specific functions regulated by these isoforms and their mechanism of activation and action. In the present review, we discuss results from recent studies that have provided some answers to these questions. 2014 Journal Article http://hdl.handle.net/20.500.11937/36636 10.1042/BST20140140 Portland Press restricted |
| spellingShingle | Maffucci, T. Falasca, Marco New insight into the intracellular roles of class II phosphoinositide 3-kinases |
| title | New insight into the intracellular roles of class II phosphoinositide 3-kinases |
| title_full | New insight into the intracellular roles of class II phosphoinositide 3-kinases |
| title_fullStr | New insight into the intracellular roles of class II phosphoinositide 3-kinases |
| title_full_unstemmed | New insight into the intracellular roles of class II phosphoinositide 3-kinases |
| title_short | New insight into the intracellular roles of class II phosphoinositide 3-kinases |
| title_sort | new insight into the intracellular roles of class ii phosphoinositide 3-kinases |
| url | http://hdl.handle.net/20.500.11937/36636 |