Ultrasound characterization of medial gastrocnemius tissue composition in children with spastic cerebral palsy
Introduction: In this study we aimed to characterize muscle composition of the medial gastrocnemius in children with spastic cerebral palsy (SCP) using quantitative ultrasound. Methods: Forty children with SCP, aged 4–14 years, participated in this study. Children were grouped according to the gross...
| Main Authors: | , , , , , |
|---|---|
| Format: | Journal Article |
| Published: |
John Wiley & Sons, Inc
2015
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/36589 |
| _version_ | 1848754812641869824 |
|---|---|
| author | Pitcher, C. Elliott, Catherine Panizzolo, F. Valentine, J. Stannage, K. Reid, S. |
| author_facet | Pitcher, C. Elliott, Catherine Panizzolo, F. Valentine, J. Stannage, K. Reid, S. |
| author_sort | Pitcher, C. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Introduction: In this study we aimed to characterize muscle composition of the medial gastrocnemius in children with spastic cerebral palsy (SCP) using quantitative ultrasound. Methods: Forty children with SCP, aged 4–14 years, participated in this study. Children were grouped according to the gross motor function classification system (GMFCS I–V) and compared with a cohort of age- and gender-matched, typically developing children (TD; n = 12). Ultrasound scans were taken of the medial gastrocnemius. Images were then characterized using grayscale statistics to determine mean echo intensity (EI) and the size and number of spatially connected homogeneous regions (i.e., blobs). Results: Significant differences in skeletal muscle composition were found between children with SCP and their TD peers. Children classified as GMFCS III consistently exhibited the highest EI and blob area. Conclusions: This study demonstrates altered tissue composition in children with SCP visualized using ultrasound. Further work is required to determine the pathophysiology contributing to these alterations in SCP. |
| first_indexed | 2025-11-14T08:46:22Z |
| format | Journal Article |
| id | curtin-20.500.11937-36589 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:46:22Z |
| publishDate | 2015 |
| publisher | John Wiley & Sons, Inc |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-365892017-09-13T15:28:25Z Ultrasound characterization of medial gastrocnemius tissue composition in children with spastic cerebral palsy Pitcher, C. Elliott, Catherine Panizzolo, F. Valentine, J. Stannage, K. Reid, S. gross motor function quantitative muscle ultrasound children spastic cerebral palsy mean echo intensity Introduction: In this study we aimed to characterize muscle composition of the medial gastrocnemius in children with spastic cerebral palsy (SCP) using quantitative ultrasound. Methods: Forty children with SCP, aged 4–14 years, participated in this study. Children were grouped according to the gross motor function classification system (GMFCS I–V) and compared with a cohort of age- and gender-matched, typically developing children (TD; n = 12). Ultrasound scans were taken of the medial gastrocnemius. Images were then characterized using grayscale statistics to determine mean echo intensity (EI) and the size and number of spatially connected homogeneous regions (i.e., blobs). Results: Significant differences in skeletal muscle composition were found between children with SCP and their TD peers. Children classified as GMFCS III consistently exhibited the highest EI and blob area. Conclusions: This study demonstrates altered tissue composition in children with SCP visualized using ultrasound. Further work is required to determine the pathophysiology contributing to these alterations in SCP. 2015 Journal Article http://hdl.handle.net/20.500.11937/36589 10.1002/mus.24549 John Wiley & Sons, Inc restricted |
| spellingShingle | gross motor function quantitative muscle ultrasound children spastic cerebral palsy mean echo intensity Pitcher, C. Elliott, Catherine Panizzolo, F. Valentine, J. Stannage, K. Reid, S. Ultrasound characterization of medial gastrocnemius tissue composition in children with spastic cerebral palsy |
| title | Ultrasound characterization of medial gastrocnemius tissue composition in children with spastic cerebral palsy |
| title_full | Ultrasound characterization of medial gastrocnemius tissue composition in children with spastic cerebral palsy |
| title_fullStr | Ultrasound characterization of medial gastrocnemius tissue composition in children with spastic cerebral palsy |
| title_full_unstemmed | Ultrasound characterization of medial gastrocnemius tissue composition in children with spastic cerebral palsy |
| title_short | Ultrasound characterization of medial gastrocnemius tissue composition in children with spastic cerebral palsy |
| title_sort | ultrasound characterization of medial gastrocnemius tissue composition in children with spastic cerebral palsy |
| topic | gross motor function quantitative muscle ultrasound children spastic cerebral palsy mean echo intensity |
| url | http://hdl.handle.net/20.500.11937/36589 |