Probucol Suppresses Enterocytic Accumulation of Amyloid-β Induced by Saturated Fat and Cholesterol Feeding

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Probucol Suppresses Enterocytic Accumulation of Amyloid-β Induced by Saturated Fat and Cholesterol Feeding

Amyloid-β (Aβ) is secreted from lipogenic organs such as intestine and liver as an apolipoprotein of nascent triacylglycerol rich lipoproteins. Chronically elevated plasma Aβ may compromise cerebrovascular integrity and exacerbate amyloidosis—a hallmark feature of Alzheimer’s disease (AD). Probucol...

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Bibliographic Details
Main Authors:	Pallebage-Gamarallage, Menuka, Galloway, Susan, Takechi, Ryusuke, Dhaliwal, Satvinder, Mamo, John
Format:	Journal Article
Published:	Springer 2011
Online Access:	http://hdl.handle.net/20.500.11937/36581

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