Continuous renal replacement treatment and the 'bleeding patient'

A women suspected of intra-abdominal bleeding with end-stage renal failure requiring maintenance haemodialysis was treated with continuous veno-venous haemodiafiltration in the intensive care unit. The use of citrate restricted to the extracorporeal circuit maintained continuity of treatment and avo...

Full description

Bibliographic Details
Main Authors: Davies, Hugh, Leslie, Gavin, Morgan, D.
Format: Journal Article
Published: British Medical Journal Publishing Group 2010
Online Access:http://hdl.handle.net/20.500.11937/36389
_version_ 1848754756407787520
author Davies, Hugh
Leslie, Gavin
Morgan, D.
author_facet Davies, Hugh
Leslie, Gavin
Morgan, D.
author_sort Davies, Hugh
building Curtin Institutional Repository
collection Online Access
description A women suspected of intra-abdominal bleeding with end-stage renal failure requiring maintenance haemodialysis was treated with continuous veno-venous haemodiafiltration in the intensive care unit. The use of citrate restricted to the extracorporeal circuit maintained continuity of treatment and avoided the adverse affects of systemic anticoagulation. Regional citrate anticoagulation was achieved using the 'modified' Alabama Protocol. A description of the protocol is included along with troubleshooting instructions. Violations of the protocol challenged the adequacy of workforce training and patient monitoring, which saw systemic ionised calcium level reach 0.62 mmol/litre and base deficit drop -14.7. After protocol transgressions were corrected the patient was successfully treated and satisfactory biochemical control achieved without placing the patient at increased risk of bleeding. Training and vigilance in the use of citrate is essential to maintain patient safety.
first_indexed 2025-11-14T08:45:28Z
format Journal Article
id curtin-20.500.11937-36389
institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T08:45:28Z
publishDate 2010
publisher British Medical Journal Publishing Group
recordtype eprints
repository_type Digital Repository
spelling curtin-20.500.11937-363892018-06-18T01:59:41Z Continuous renal replacement treatment and the 'bleeding patient' Davies, Hugh Leslie, Gavin Morgan, D. A women suspected of intra-abdominal bleeding with end-stage renal failure requiring maintenance haemodialysis was treated with continuous veno-venous haemodiafiltration in the intensive care unit. The use of citrate restricted to the extracorporeal circuit maintained continuity of treatment and avoided the adverse affects of systemic anticoagulation. Regional citrate anticoagulation was achieved using the 'modified' Alabama Protocol. A description of the protocol is included along with troubleshooting instructions. Violations of the protocol challenged the adequacy of workforce training and patient monitoring, which saw systemic ionised calcium level reach 0.62 mmol/litre and base deficit drop -14.7. After protocol transgressions were corrected the patient was successfully treated and satisfactory biochemical control achieved without placing the patient at increased risk of bleeding. Training and vigilance in the use of citrate is essential to maintain patient safety. 2010 Journal Article http://hdl.handle.net/20.500.11937/36389 10.1136/bcr.01.2009.1523 British Medical Journal Publishing Group restricted
spellingShingle Davies, Hugh
Leslie, Gavin
Morgan, D.
Continuous renal replacement treatment and the 'bleeding patient'
title Continuous renal replacement treatment and the 'bleeding patient'
title_full Continuous renal replacement treatment and the 'bleeding patient'
title_fullStr Continuous renal replacement treatment and the 'bleeding patient'
title_full_unstemmed Continuous renal replacement treatment and the 'bleeding patient'
title_short Continuous renal replacement treatment and the 'bleeding patient'
title_sort continuous renal replacement treatment and the 'bleeding patient'
url http://hdl.handle.net/20.500.11937/36389