Synthesis and in vitro evaluation of bone-seeking superparamagnetic iron oxide nanoparticles as contrast agents for imaging bone metabolic activity

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Synthesis and in vitro evaluation of bone-seeking superparamagnetic iron oxide nanoparticles as contrast agents for imaging bone metabolic activity

In this article, we report the synthesis and in vitro evaluation of a new class of nonionizing bone-targeting contrast agents based on bisphosphonate-conjugated superparamagnetic iron oxide nanoparticles (SPIONs), for use in imaging of bone turnover with magnetic resonance imaging (MRI). Similar to...

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Bibliographic Details
Main Authors:	Panahifar, A., Mahmoudi, M., Doschak, Michael
Format:	Journal Article
Published:	American Chemical Society 2013
Subjects:	contrast agent bisphosphonate superparamagnetic iron oxide nanoparticles selective binding MRI bone diagnosis osteoarthritis
Online Access:	http://hdl.handle.net/20.500.11937/36090

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