Therapeutic impact of human serum albumin-thioredoxin fusion protein on influenza virus-induced lung injury mice
Reactive oxygen species (ROS) are the primary pathogenic molecules produced in viral lung infections. We previously reported on the use of a recombinant human serum albumin (HSA)-thioredoxin 1 (Trx) fusion protein (HSA-Trx) for extending the half-life Trx, an endogenous protein with anti-oxidant pro...
| Main Authors: | Tanaka, R., Ishima, Y., Enoki, Y., Kimachi, K., Shirai, T., Watanabe, H., Chuang, Victor, Maruyama, T., Otagiri, M. |
|---|---|
| Format: | Journal Article |
| Published: |
Frontiers Research Foundation
2014
|
| Online Access: | http://hdl.handle.net/20.500.11937/36079 |
Similar Items
Human serum albumin-thioredoxin fusion protein with long blood retention property is effective in suppressing lung injury
by: Furukawa, M., et al.
Published: (2011)
by: Furukawa, M., et al.
Published: (2011)
Albumin fusion of thioredoxin - The production and evaluation of its biological activity for potential therapeutic applications
by: Ikuta, S., et al.
Published: (2010)
by: Ikuta, S., et al.
Published: (2010)
Long-acting human serum albumin-thioredoxin fusion protein suppresses bleomycin-induced pulmonary fibrosis progression
by: Tanaka, R., et al.
Published: (2013)
by: Tanaka, R., et al.
Published: (2013)
Albumin fusion prolongs the antioxidant and anti-inflammatory activities of thioredoxin in mice with acetaminophen-induced hepatitis
by: Tanaka, R., et al.
Published: (2014)
by: Tanaka, R., et al.
Published: (2014)
A human serum albumin–thioredoxin fusion protein prevents experimental contrast-induced nephropathy
by: Kodama, A., et al.
Published: (2013)
by: Kodama, A., et al.
Published: (2013)
Thioredoxin-albumin fusion protein prevents copper enhanced zinc-induced neurotoxicity via its antioxidative activity
by: Tanaka, K., et al.
Published: (2018)
by: Tanaka, K., et al.
Published: (2018)
Albumin fusion renders thioredoxin an effective anti-oxidative and anti-inflammatory agent for preventing cisplatin-induced nephrotoxicity
by: Kodama, A., et al.
Published: (2014)
by: Kodama, A., et al.
Published: (2014)
Pleiotropic effects of levofloxacin, fluoroquinolone antibiotics, against influenza virus-induced lung injury
by: Enoki, Y., et al.
Published: (2015)
by: Enoki, Y., et al.
Published: (2015)
Redox properties of serum albumin
by: Anraku, M., et al.
Published: (2013)
by: Anraku, M., et al.
Published: (2013)
Potential use of human serum albumin as a drug delivery systems
by: Ishima, Y., et al.
Published: (2015)
by: Ishima, Y., et al.
Published: (2015)
Recombinant human serum albumin
by: Chuang, Victor, et al.
Published: (2007)
by: Chuang, Victor, et al.
Published: (2007)
Pharmacokinetically modified human serum albumin based therapeutic design and development
by: Taguchi, K., et al.
Published: (2015)
by: Taguchi, K., et al.
Published: (2015)
Stereoselective Binding of Human Serum Albumin
by: Chuang, Victor, et al.
Published: (2006)
by: Chuang, Victor, et al.
Published: (2006)
A novel S-sulfhydrated human serum albumin preparation suppresses melanin synthesis
by: Ikeda, M., et al.
Published: (2018)
by: Ikeda, M., et al.
Published: (2018)
Improved anticancer effects of albumin-bound paclitaxel nanoparticle via augmentation of EPR effect and albumin-protein interactions using S-nitrosated human serum albumin dimer
by: Kinoshita, R., et al.
Published: (2017)
by: Kinoshita, R., et al.
Published: (2017)
Apoptosis induction of poly-S-nitrosated human serum albumin in resistant solid tumor under hypoxia can be restored by phosphodiesterase 5 inhibition
by: Ikeda, M., et al.
Published: (2016)
by: Ikeda, M., et al.
Published: (2016)
Pharmaceutically Important Pre- and Posttranslational Modifications on Human Serum Albumin
by: Otagiri, M., et al.
Published: (2009)
by: Otagiri, M., et al.
Published: (2009)
Pharmaceutical Aspects of the Recombinant Human Serum Albumin Dimer: Structural Characteristics, Biological Properties, and Medical Applications
by: Taguchi, K., et al.
Published: (2012)
by: Taguchi, K., et al.
Published: (2012)
Human serum albumin hydropersulfide is a potent reactive oxygen species scavenger in oxidative stress conditions such as chronic kidney disease
by: Shibata, A., et al.
Published: (2016)
by: Shibata, A., et al.
Published: (2016)
How Do Fatty Acids Cause Allosteric Binding of Drugs to Human Serum Albumin?
by: Chuang, Victor, et al.
Published: (2002)
by: Chuang, Victor, et al.
Published: (2002)
Differential Effects of Methoxy Group on the Interaction of Curcuminoids with Two Major Ligand Binding Sites of Human Serum Albumin
by: Sato, H., et al.
Published: (2014)
by: Sato, H., et al.
Published: (2014)
Arginine 485 of human serum albumin interacts with the benzophenone moiety of ketoprofen in the binding pocket of subdomain III A and III B
by: Kaneko, K., et al.
Published: (2012)
by: Kaneko, K., et al.
Published: (2012)
Practical Aspects of the Ligand-Binding and Enzymatic Properties of Human Serum Albumin
by: Kragh-Hansen, U., et al.
Published: (2002)
by: Kragh-Hansen, U., et al.
Published: (2002)
Albumin-drug interaction and its clinical implication
by: Yamasaki, K., et al.
Published: (2013)
by: Yamasaki, K., et al.
Published: (2013)
Cys34-cysteinylated human serum albumin is a sensitive plasma marker in oxidative stress-related chronic diseases
by: Nagumo, K., et al.
Published: (2014)
by: Nagumo, K., et al.
Published: (2014)
Biological characteristics of two lysines on human serum albumin in the high-affinity binding of 4Z, 15Z-bilirubin-IXa revealed by phage display
by: Minomo, A., et al.
Published: (2011)
by: Minomo, A., et al.
Published: (2011)
S-Nitrosated human serum albumin dimer as novel nano-EPR enhancer applied to macromolecular anti-tumor drugs such as micelles and liposomes
by: Kinoshita, R., et al.
Published: (2015)
by: Kinoshita, R., et al.
Published: (2015)
Biological characteristics of two lysines on human serum albumin in the high affinity binding of m4Z,15Z-bilirubin-Ix[alpha] revealed by phage display
by: Minomo, A., et al.
Published: (2011)
by: Minomo, A., et al.
Published: (2011)
Biological characteristics of two lysines on human serum albumin in the high affinity binding of m4Z,15Z-bilirubin-Ix[alpha] revealed by phage display
by: Minomo, A., et al.
Published: (2011)
by: Minomo, A., et al.
Published: (2011)
Flunitrazepam, a 7-nitro-1,4-benzodiazepine that is unable to bind to the indole-benzodiazepine site of human serum albumin
by: Chuang, Victor, et al.
Published: (2001)
by: Chuang, Victor, et al.
Published: (2001)
The potential of a cross-linked human serum albumin dimer in diabetic rats as an augmenting agent for antidiabetic drugs
by: Taguchi, K., et al.
Published: (2015)
by: Taguchi, K., et al.
Published: (2015)
Design and tuning of a cell-penetrating albumin derivative as a versatile nanovehicle for intracellular drug delivery
by: Ichimizu, S., et al.
Published: (2018)
by: Ichimizu, S., et al.
Published: (2018)
Renoprotective effect of long acting thioredoxin by modulating oxidative stress and macrophage migration inhibitory factor against rhabdomyolysis-Associated acute kidney injury
by: Nishida, K., et al.
Published: (2015)
by: Nishida, K., et al.
Published: (2015)
Albumin domain II mutant with high bilirubin binding affinity has a great potential as serum bilirubin excretion enhancer for hyperbilirubinemia treatment
by: Minomo, Ai, et al.
Published: (2013)
by: Minomo, Ai, et al.
Published: (2013)
Histidine146 of Human Serum Albumin Plays a Prominent Role at the Interface of Subdomains IA and IIA in Allosteric Ligand Binding
by: Kaneko, K., et al.
Published: (2011)
by: Kaneko, K., et al.
Published: (2011)
Cross-linked human serum albumin dimer has the potential for use as a plasma-retaining agent for the fatty acid-conjugated antidiabetic drugs
by: Taguchi, K., et al.
Published: (2015)
by: Taguchi, K., et al.
Published: (2015)
Polythiol-containing, recombinant mannosylated-albumin is a superior CD68+/CD206+ Kupffer cell-targeted nano-antioxidant for the treatment of two acute hepatitis models
by: Maeda, H., et al.
Published: (2015)
by: Maeda, H., et al.
Published: (2015)
Long chain fatty acids alter the interactive binding of ligands to the two principal drug binding sites of human serum albumin
by: Yamasaki, K., et al.
Published: (2017)
by: Yamasaki, K., et al.
Published: (2017)
Crystallographic analysis of the ternary complex of octanoate and N-acetyl-l-methionine with human serum albumin reveals the mode of their stabilizing interactions
by: Kawai, A., et al.
Published: (2017)
by: Kawai, A., et al.
Published: (2017)
Helix 6 of subdomain III A of human serum albumin is the region primarily photolabeled by ketoprofen, an arylpropionic acid NSAID containing a benzophenone moiety
by: Chuang, Victor, et al.
Published: (1999)
by: Chuang, Victor, et al.
Published: (1999)
Similar Items
-
Human serum albumin-thioredoxin fusion protein with long blood retention property is effective in suppressing lung injury
by: Furukawa, M., et al.
Published: (2011) -
Albumin fusion of thioredoxin - The production and evaluation of its biological activity for potential therapeutic applications
by: Ikuta, S., et al.
Published: (2010) -
Long-acting human serum albumin-thioredoxin fusion protein suppresses bleomycin-induced pulmonary fibrosis progression
by: Tanaka, R., et al.
Published: (2013) -
Albumin fusion prolongs the antioxidant and anti-inflammatory activities of thioredoxin in mice with acetaminophen-induced hepatitis
by: Tanaka, R., et al.
Published: (2014) -
A human serum albumin–thioredoxin fusion protein prevents experimental contrast-induced nephropathy
by: Kodama, A., et al.
Published: (2013)