CfT-1, An LTR-Retrotransposon in Cladosporium fulvum, a fungal pathogen of tomato

A retrotransposon from the fungal tomato pathogen Cladosporium fulvum (syn. Fulvia fulva) has been isolated and characterised. It is 6968 by in length and bounded by identical long terminal repeats of 427 bp; 5 by target-site duplications were found. Putative first- and second-strand primer binding...

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Main Authors: McHale, M., Roberts, I., Noble, S., Beaumont, C., Whitehead, M., Seth, D., Oliver, Richard
Format: Journal Article
Published: 1992
Online Access:http://hdl.handle.net/20.500.11937/35927
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author McHale, M.
Roberts, I.
Noble, S.
Beaumont, C.
Whitehead, M.
Seth, D.
Oliver, Richard
author_facet McHale, M.
Roberts, I.
Noble, S.
Beaumont, C.
Whitehead, M.
Seth, D.
Oliver, Richard
author_sort McHale, M.
building Curtin Institutional Repository
collection Online Access
description A retrotransposon from the fungal tomato pathogen Cladosporium fulvum (syn. Fulvia fulva) has been isolated and characterised. It is 6968 by in length and bounded by identical long terminal repeats of 427 bp; 5 by target-site duplications were found. Putative first- and second-strand primer binding sites were identified. Three long open reading frames (ORFs) are predicted from the sequence. The first has homology to retroviral gag genes. The second includes sequences homologous to protease, reverse transcriptase, RNAse H and integrase, in that order. Sequence comparisons of the predicted ORFs indicate that this element is closely related to the gypsy class of LTR retrotransposons. Races of the pathogen exhibit polymorphisms in their complement of at least 25 copies of the sequence. Virus-like particles which co-sediment with reverse transcriptase activity were observed in homogenates of the fungus. This is the first report of an LTR retrotransposon in a filamentous fungus.
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publishDate 1992
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spelling curtin-20.500.11937-359272017-09-13T15:51:05Z CfT-1, An LTR-Retrotransposon in Cladosporium fulvum, a fungal pathogen of tomato McHale, M. Roberts, I. Noble, S. Beaumont, C. Whitehead, M. Seth, D. Oliver, Richard A retrotransposon from the fungal tomato pathogen Cladosporium fulvum (syn. Fulvia fulva) has been isolated and characterised. It is 6968 by in length and bounded by identical long terminal repeats of 427 bp; 5 by target-site duplications were found. Putative first- and second-strand primer binding sites were identified. Three long open reading frames (ORFs) are predicted from the sequence. The first has homology to retroviral gag genes. The second includes sequences homologous to protease, reverse transcriptase, RNAse H and integrase, in that order. Sequence comparisons of the predicted ORFs indicate that this element is closely related to the gypsy class of LTR retrotransposons. Races of the pathogen exhibit polymorphisms in their complement of at least 25 copies of the sequence. Virus-like particles which co-sediment with reverse transcriptase activity were observed in homogenates of the fungus. This is the first report of an LTR retrotransposon in a filamentous fungus. 1992 Journal Article http://hdl.handle.net/20.500.11937/35927 10.1007/BF00265429 restricted
spellingShingle McHale, M.
Roberts, I.
Noble, S.
Beaumont, C.
Whitehead, M.
Seth, D.
Oliver, Richard
CfT-1, An LTR-Retrotransposon in Cladosporium fulvum, a fungal pathogen of tomato
title CfT-1, An LTR-Retrotransposon in Cladosporium fulvum, a fungal pathogen of tomato
title_full CfT-1, An LTR-Retrotransposon in Cladosporium fulvum, a fungal pathogen of tomato
title_fullStr CfT-1, An LTR-Retrotransposon in Cladosporium fulvum, a fungal pathogen of tomato
title_full_unstemmed CfT-1, An LTR-Retrotransposon in Cladosporium fulvum, a fungal pathogen of tomato
title_short CfT-1, An LTR-Retrotransposon in Cladosporium fulvum, a fungal pathogen of tomato
title_sort cft-1, an ltr-retrotransposon in cladosporium fulvum, a fungal pathogen of tomato
url http://hdl.handle.net/20.500.11937/35927