PLUMED: a portable plugin for free-energy calculations with molecular dynamics

Here we present a program aimed at free-energy calculations in molecular systems. It consists of aseries of routines that can be interfaced with the most popular classical molecular dynamics (MD) codes through a simple patching procedure. This leaves the possibility for the user to exploit many diff...

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Main Authors: Bonomi, M., Branduardi, D., Bussi, G., Camilloni, C., Provasi, D., Raiteri, Paolo, Donadio, D., Marinelli, F., Pietrucci, F., Broglia, R., Parrinello, M.
Format: Journal Article
Published: Elsevier 2009
Online Access:http://hdl.handle.net/20.500.11937/35745
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author Bonomi, M.
Branduardi, D.
Bussi, G.
Camilloni, C.
Provasi, D.
Raiteri, Paolo
Donadio, D.
Marinelli, F.
Pietrucci, F.
Broglia, R.
Parrinello, M.
author_facet Bonomi, M.
Branduardi, D.
Bussi, G.
Camilloni, C.
Provasi, D.
Raiteri, Paolo
Donadio, D.
Marinelli, F.
Pietrucci, F.
Broglia, R.
Parrinello, M.
author_sort Bonomi, M.
building Curtin Institutional Repository
collection Online Access
description Here we present a program aimed at free-energy calculations in molecular systems. It consists of aseries of routines that can be interfaced with the most popular classical molecular dynamics (MD) codes through a simple patching procedure. This leaves the possibility for the user to exploit many different MD engines depending on the system simulated and on the computational resources available. Freeenergy calculations can be performed as a function of many collective variables, with a particular focus on biological problems, and using state-of-the-art methods such as metadynamics, umbrella sampling and Jarzynski-equation based steered MD. The present software, written in ANSI-C language, can be easily interfaced with both Fortran and C/C++ codes.
first_indexed 2025-11-14T08:42:39Z
format Journal Article
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institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T08:42:39Z
publishDate 2009
publisher Elsevier
recordtype eprints
repository_type Digital Repository
spelling curtin-20.500.11937-357452017-09-13T16:07:46Z PLUMED: a portable plugin for free-energy calculations with molecular dynamics Bonomi, M. Branduardi, D. Bussi, G. Camilloni, C. Provasi, D. Raiteri, Paolo Donadio, D. Marinelli, F. Pietrucci, F. Broglia, R. Parrinello, M. Here we present a program aimed at free-energy calculations in molecular systems. It consists of aseries of routines that can be interfaced with the most popular classical molecular dynamics (MD) codes through a simple patching procedure. This leaves the possibility for the user to exploit many different MD engines depending on the system simulated and on the computational resources available. Freeenergy calculations can be performed as a function of many collective variables, with a particular focus on biological problems, and using state-of-the-art methods such as metadynamics, umbrella sampling and Jarzynski-equation based steered MD. The present software, written in ANSI-C language, can be easily interfaced with both Fortran and C/C++ codes. 2009 Journal Article http://hdl.handle.net/20.500.11937/35745 10.1016/j.cpc.2009.05.011 Elsevier fulltext
spellingShingle Bonomi, M.
Branduardi, D.
Bussi, G.
Camilloni, C.
Provasi, D.
Raiteri, Paolo
Donadio, D.
Marinelli, F.
Pietrucci, F.
Broglia, R.
Parrinello, M.
PLUMED: a portable plugin for free-energy calculations with molecular dynamics
title PLUMED: a portable plugin for free-energy calculations with molecular dynamics
title_full PLUMED: a portable plugin for free-energy calculations with molecular dynamics
title_fullStr PLUMED: a portable plugin for free-energy calculations with molecular dynamics
title_full_unstemmed PLUMED: a portable plugin for free-energy calculations with molecular dynamics
title_short PLUMED: a portable plugin for free-energy calculations with molecular dynamics
title_sort plumed: a portable plugin for free-energy calculations with molecular dynamics
url http://hdl.handle.net/20.500.11937/35745