Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIba.

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Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIba.

BACKGROUND: Platelets are essential for maintaining haemostasis and play a key role in the pathogenesis of cardiovascular disease. Upon ligation of platelet receptors through subendothelial matrix proteins, intracellular reactive oxygen species (ROS) are generated, further amplifying the platelet ac...

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Bibliographic Details
Main Authors:	Carrim, N., Arthur, J., Hamilton, J., Gardiner, E., Andrews, R., Moran, N., Berndt, Michael, Metharom, Pat
Format:	Journal Article
Published:	2015
Online Access:	http://hdl.handle.net/20.500.11937/35412

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