Relationship between brain structure on magnetic resonance imaging and motor outcomes in children with cerebral palsy: A systematic review

Magnetic resonance imaging (MRI) is recommended in all children with cerebral palsy (CP) where the aetiology has not been established, and the major presenting problem in CP is reduced motor capacity. A systematic review of the literature was performed to investigate the relationship between brain s...

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Main Authors: Arnfield, E., Guzzetta, A., Boyd, Roslyn
Format: Journal Article
Published: 2013
Online Access:http://hdl.handle.net/20.500.11937/34945
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author Arnfield, E.
Guzzetta, A.
Boyd, Roslyn
author_facet Arnfield, E.
Guzzetta, A.
Boyd, Roslyn
author_sort Arnfield, E.
building Curtin Institutional Repository
collection Online Access
description Magnetic resonance imaging (MRI) is recommended in all children with cerebral palsy (CP) where the aetiology has not been established, and the major presenting problem in CP is reduced motor capacity. A systematic review of the literature was performed to investigate the relationship between brain structure on MRI and motor outcomes in children with CP. A total of 37 studies met inclusion criteria, and were analysed in terms of (a) population characteristics, (b) MRI data, (c) motor outcome data, and (d) the relationship between MRI data and motor outcomes. All studies used a qualitative system to classify brain lesions; however, few reported information about the location and extent of lesions. Valid and reliable classifications of motor abilities were not always used, and three studies did not link motor findings to MRI features. There was, however, a relationship between the type of brain lesion on MRI and two specific motor outcomes, namely gross motor functional classification (using GMFCS) and motor type. This relationship could aid in the prediction and optimisation of early interventions for children with CP. There is also need for a quantitative MRI classification measure which includes detailed information about the location and severity of lesions. © 2013 Elsevier Ltd.
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spelling curtin-20.500.11937-349452017-09-13T15:28:26Z Relationship between brain structure on magnetic resonance imaging and motor outcomes in children with cerebral palsy: A systematic review Arnfield, E. Guzzetta, A. Boyd, Roslyn Magnetic resonance imaging (MRI) is recommended in all children with cerebral palsy (CP) where the aetiology has not been established, and the major presenting problem in CP is reduced motor capacity. A systematic review of the literature was performed to investigate the relationship between brain structure on MRI and motor outcomes in children with CP. A total of 37 studies met inclusion criteria, and were analysed in terms of (a) population characteristics, (b) MRI data, (c) motor outcome data, and (d) the relationship between MRI data and motor outcomes. All studies used a qualitative system to classify brain lesions; however, few reported information about the location and extent of lesions. Valid and reliable classifications of motor abilities were not always used, and three studies did not link motor findings to MRI features. There was, however, a relationship between the type of brain lesion on MRI and two specific motor outcomes, namely gross motor functional classification (using GMFCS) and motor type. This relationship could aid in the prediction and optimisation of early interventions for children with CP. There is also need for a quantitative MRI classification measure which includes detailed information about the location and severity of lesions. © 2013 Elsevier Ltd. 2013 Journal Article http://hdl.handle.net/20.500.11937/34945 10.1016/j.ridd.2013.03.031 restricted
spellingShingle Arnfield, E.
Guzzetta, A.
Boyd, Roslyn
Relationship between brain structure on magnetic resonance imaging and motor outcomes in children with cerebral palsy: A systematic review
title Relationship between brain structure on magnetic resonance imaging and motor outcomes in children with cerebral palsy: A systematic review
title_full Relationship between brain structure on magnetic resonance imaging and motor outcomes in children with cerebral palsy: A systematic review
title_fullStr Relationship between brain structure on magnetic resonance imaging and motor outcomes in children with cerebral palsy: A systematic review
title_full_unstemmed Relationship between brain structure on magnetic resonance imaging and motor outcomes in children with cerebral palsy: A systematic review
title_short Relationship between brain structure on magnetic resonance imaging and motor outcomes in children with cerebral palsy: A systematic review
title_sort relationship between brain structure on magnetic resonance imaging and motor outcomes in children with cerebral palsy: a systematic review
url http://hdl.handle.net/20.500.11937/34945