A Novel Erythromycin Resistance Plasmid from Bacillus Sp. Strain HS24, Isolated from the Marine Sponge Haliclona Simulans

A Novel Erythromycin Resistance Plasmid from Bacillus Sp. Strain HS24, Isolated from the Marine Sponge Haliclona Simulans

A better understanding of the origin and natural reservoirs of resistance determinants is fundamental to efficiently tackle antibiotic resistance. This paper reports the identification of a novel 5.8 kb erythromycin resistance plasmid, from Bacillus sp. HS24 isolated from the marine sponge Haliclona...

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Bibliographic Details
Main Authors: Barbosa, T., Phelan, R., Leong, D., Morrissey, J., Adams, C., Dobson, A., O'Gara, Fergal
Format: Journal Article
Published: Public Library of Science 2014
Subjects:
antibiotics
Bacillus subtilis
sequence databases
antibiotic resistance
ribosomal RNA
sponges
Erythromycin
Bacillus
Online Access:http://hdl.handle.net/20.500.11937/34783
Description
Summary:A better understanding of the origin and natural reservoirs of resistance determinants is fundamental to efficiently tackle antibiotic resistance. This paper reports the identification of a novel 5.8 kb erythromycin resistance plasmid, from Bacillus sp. HS24 isolated from the marine sponge Haliclona simulans. pBHS24B has a mosaic structure and carries the erythromycin resistance gene erm(T). This is the first report of an erythromycin resistance plasmid from a sponge associated bacteria and of the Erm(T) determinant in the genus Bacillus.

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