Suberoylanilide hydroxamic acid – a potential epigenetic therapeutic agent for lung fibrosis?
Pulmonary fibrosis represents a fatal stage of interstitial lung diseases of known and idiopathic aetiology. No effective therapy is currently available. Based on an indication-discovery approach we present novel in vitro evidence that the histone deacetylases inhibitor suberoylanilide hydroxamic ac...
| Main Authors: | Wang, Z., Chen, C., Finger, S., Kwajah, M., Jung, M., Schwarz, H., Swanson, N., Lareu, Ricardo, Raghunath, M. |
|---|---|
| Format: | Journal Article |
| Published: |
European Respiratory Society
2009
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/34604 |
Similar Items
Interplay between EZH2 and G9a regulates CXCL10 gene repression in idiopathic pulmonary fibrosis
by: Coward, William R., et al.
Published: (2017)
by: Coward, William R., et al.
Published: (2017)
Application of a human primary epithelial-fibroblast co-culture system to study fibrosis
by: Richardson, Jaineeta
Published: (2017)
by: Richardson, Jaineeta
Published: (2017)
International comparative epidemiology of idiopathic pulmonary fibrosis
by: Hutchinson, John
Published: (2017)
by: Hutchinson, John
Published: (2017)
Defining the mechanism of galectin-3-mediated TGF-β1 activation and its role in lung fibrosis
by: Calver, J.F.
Published: (2023)
by: Calver, J.F.
Published: (2023)
The Scar-in-a-Jar: studying potential anti?brotic compounds from the epigenetic to extracellular level in a single well
by: Chen, C., et al.
Published: (2009)
by: Chen, C., et al.
Published: (2009)
Suberanilohydroxamic acid prevents TGF-β1-induced COX-2 repression in human lung fibroblasts post-transcriptionally by TIA-1 downregulation
by: Pasini, Alice, et al.
Published: (2018)
by: Pasini, Alice, et al.
Published: (2018)
Preparation of potent and selective αvβ6 integrin inhibitors for the treatment of idiopathic pulmonary fibrosis and synthetic approaches towards the total synthesis of mescengricin
by: Robinson, Henry Duncan
Published: (2021)
by: Robinson, Henry Duncan
Published: (2021)
Global incidence and mortality of idiopathic pulmonary fibrosis: a systematic review
by: Hutchinson, John P., et al.
Published: (2015)
by: Hutchinson, John P., et al.
Published: (2015)
Refining in-vivo models of pulmonary fibrosis
by: Habgood, Anthony
Published: (2018)
by: Habgood, Anthony
Published: (2018)
Evaluation of activity limitation in patients with idiopathic pulmonary fibrosis grouped according to Medical Research Council Dyspnea Grade
by: Kozu, R., et al.
Published: (2014)
by: Kozu, R., et al.
Published: (2014)
Increasing global mortality from idiopathic pulmonary fibrosis in the twenty-first century
by: Hutchinson, John P., et al.
Published: (2014)
by: Hutchinson, John P., et al.
Published: (2014)
Enzymatic syntheses, characterizations and applications of fatty hydroxamic acid derivatives from canola and palm oils
by: Jahangirian, Hossein
Published: (2012)
by: Jahangirian, Hossein
Published: (2012)
Developing stromal instructive niches to promote wound healing
by: Latif, Arsalan
Published: (2021)
by: Latif, Arsalan
Published: (2021)
The role of Interleukin-33 in the development of idiopathic pulmonary fibrosis
by: Stephenson, Katherine
Published: (2021)
by: Stephenson, Katherine
Published: (2021)
Investigations into novel small molecules as potential treatments for idiopathic pulmonary fibrosis and malaria
by: Park, Jozef
Published: (2022)
by: Park, Jozef
Published: (2022)
Spatiotemporal regulation of anti-remodelling signalling pathways in primary human lung fibroblasts
by: Roberts, Maxine
Published: (2020)
by: Roberts, Maxine
Published: (2020)
Removal of Hazardous Oxyanion Pollutants by Lanthanum (Iii) Hydroxide and Lanthanum (III) - Loaded Ion Exchangers
by: Ahmed, Yehya M.
Published: (2004)
by: Ahmed, Yehya M.
Published: (2004)
cAMP mediated regulation of fibroblast to myofibroblast differentiation in idiopathic pulmonary fibrosis
by: Wright, Rebecca
Published: (2016)
by: Wright, Rebecca
Published: (2016)
Collagen solubility testing, a quality assurance step for reproducible electro-spun nano-fibre fabrication. A technical note
by: Zeugolis, D., et al.
Published: (2008)
by: Zeugolis, D., et al.
Published: (2008)
The inhibition of human lung fibroblast proliferation and differentiation by Gs-coupled receptors is not predicted by the magnitude of cAMP response
by: Roberts, Maxine J., et al.
Published: (2018)
by: Roberts, Maxine J., et al.
Published: (2018)
Preparation and application of poly(hydroxamic acid)-kenaf fiber chelating ion exchanger for the removal of chromium and nickel from aqueous solutions
by: Mohamat Yusuff, Soleha
Published: (2013)
by: Mohamat Yusuff, Soleha
Published: (2013)
The role of galectin-3 in the development of idiopathic pulmonary fibrosis
by: Parmar, Nimesh
Published: (2019)
by: Parmar, Nimesh
Published: (2019)
Histone modulation by nuclear localized meningococcal autotransporters
by: Dutta, Shoma
Published: (2020)
by: Dutta, Shoma
Published: (2020)
Effects of hypoxia and hyperoxia on the differential expression of VEGF-A isoforms and receptors in Idiopathic Pulmonary Fibrosis (IPF)
by: Barratt, Shaney L., et al.
Published: (2018)
by: Barratt, Shaney L., et al.
Published: (2018)
The role of mesenchymal G proteins in pulmonary fibrosis and lung development
by: Goodwin, Amanda T.
Published: (2021)
by: Goodwin, Amanda T.
Published: (2021)
Extraction of collagen from fish waste and determination of its physico-chemical
characteristics / Nurul Asyiraf Abdul Jabar
by: Abdul Jabar, Nurul Asyiraf
Published: (2011)
by: Abdul Jabar, Nurul Asyiraf
Published: (2011)
Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study
by: Jenkins, R. Gisli, et al.
Published: (2015)
by: Jenkins, R. Gisli, et al.
Published: (2015)
Early epigenetic reprogramming in fertilized, cloned, and parthenogenetic embryos
by: Sepulveda-Rincon, Lessly P., et al.
Published: (2016)
by: Sepulveda-Rincon, Lessly P., et al.
Published: (2016)
Essential modification of the Sircol Collagen Assay for the accurate quantification of collagen content in complex protein solutions
by: Lareu, Ricky R., et al.
Published: (2010)
by: Lareu, Ricky R., et al.
Published: (2010)
ECM crosslinking enhances fibroblast growth and protects against matrix proteolysis in lung fibrosis
by: Philp, Christopher J., et al.
Published: (2017)
by: Philp, Christopher J., et al.
Published: (2017)
Structure activity relationships of αv integrin antagonists for pulmonary fibrosis by variation in aryl substituents
by: Adams, James, et al.
Published: (2014)
by: Adams, James, et al.
Published: (2014)
Extraction of collagen from catfish (Clarias gariepnus) waste and determination of its physico-chemical properties / Normah Ismail and Nurul Asyiraf Abdul Jabar
by: Ismail, Normah, et al.
Published: (2012)
by: Ismail, Normah, et al.
Published: (2012)
Delayed publications of clinical trials in cystic fibrosis
by: Hurley, M.N., et al.
Published: (2011)
by: Hurley, M.N., et al.
Published: (2011)
Surgical lung biopsy for the diagnosis of interstitial lung disease in England: 1997-2008
by: Hutchinson, John P., et al.
Published: (2016)
by: Hutchinson, John P., et al.
Published: (2016)
Immunomodulatory action of new curcumin analogue [2,6-BIS(2,5-dimethoxybenzylidene) cyclohexanone] on major inflammatory mediator expression in activated macrophage and synovial fibroblast cells
by: Lee, Ka Heng
Published: (2012)
by: Lee, Ka Heng
Published: (2012)
Drug repurposing of clinically-approved drugs to target epithelial-mesenchymal transition using in silico analysis
by: Ong, Chun Hao
Published: (2021)
by: Ong, Chun Hao
Published: (2021)
Glutamine supplementation in cystic fibrosis: a randomized placebo-controlled trial
by: Forrester, Doug L., et al.
Published: (2015)
by: Forrester, Doug L., et al.
Published: (2015)
Redesign of collagen casings for high quality performance using food grade polysaccharides
by: Sobanwa, Motolani
Published: (2022)
by: Sobanwa, Motolani
Published: (2022)
Porous scaffolds and soft hydrogel scaffolds for soft tissue engineering
by: Yang, Yang
Published: (2018)
by: Yang, Yang
Published: (2018)
Results of antibiotic susceptibility testing do not influence clinical outcome in children with cystic fibrosis
by: Hurley, M.N., et al.
Published: (2012)
by: Hurley, M.N., et al.
Published: (2012)
Similar Items
-
Interplay between EZH2 and G9a regulates CXCL10 gene repression in idiopathic pulmonary fibrosis
by: Coward, William R., et al.
Published: (2017) -
Application of a human primary epithelial-fibroblast co-culture system to study fibrosis
by: Richardson, Jaineeta
Published: (2017) -
International comparative epidemiology of idiopathic pulmonary fibrosis
by: Hutchinson, John
Published: (2017) -
Defining the mechanism of galectin-3-mediated TGF-β1 activation and its role in lung fibrosis
by: Calver, J.F.
Published: (2023) -
The Scar-in-a-Jar: studying potential anti?brotic compounds from the epigenetic to extracellular level in a single well
by: Chen, C., et al.
Published: (2009)