Elevated levels of branched-chain amino acids have little effect on pancreatic islet cells, but L-arginine impairs function through activation of the endoplasmic reticulum stress response

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Elevated levels of branched-chain amino acids have little effect on pancreatic islet cells, but L-arginine impairs function through activation of the endoplasmic reticulum stress response

New Findings - What is the central question of this study?: Recent studies have demonstrated strong correlations between circulating branched-chain amino acid (AA) levels and insulin resistance, a predictor of susceptibility to type 2 diabetes. This study investigated how elevations in various AA co...

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Bibliographic Details
Main Authors:	Mullooly, N., Vernon, W., Smith, D., Newsholme, Philip
Format:	Journal Article
Published:	Wiley-Blackwell 2014
Online Access:	http://hdl.handle.net/20.500.11937/34577

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