A nonenzymatic sensor for xanthine based on electrospun carbon nanofibers modified electrode
Xanthine (Xa) determination is of considerable importance in clinical analysis and food quality control. Therefore, a sensitive nonenzymatic amperometric sensor for Xa based on carbon nanofibers (CNFs) has been proposed. The CNFs, which were prepared by electrospinning technique and subsequent therm...
| Main Authors: | , , , |
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| Format: | Journal Article |
| Published: |
Elsevier
2011
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| Online Access: | http://hdl.handle.net/20.500.11937/34133 |
| _version_ | 1848754139704590336 |
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| author | Tang, X. Liu, Yang Hou, H. You, T. |
| author_facet | Tang, X. Liu, Yang Hou, H. You, T. |
| author_sort | Tang, X. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Xanthine (Xa) determination is of considerable importance in clinical analysis and food quality control. Therefore, a sensitive nonenzymatic amperometric sensor for Xa based on carbon nanofibers (CNFs) has been proposed. The CNFs, which were prepared by electrospinning technique and subsequent thermal treatment, were used to modify carbon paste electrode (CNF-CPE) to construct the amperometric sensor device without any oxidation pretreatment. In application to Xa electrochemical determination, the CNF-CPE exhibited high electrocatalytic activity and fast amperometric response. Various experimental parameters, such as pH and applied potential were optimized. Under the optimal conditions, the dynamic linear range of Xa was 0.03–21.19M (R = 0.9992) with the detection limit low to 20nM (S/N= 3). With good selectivity and sensitivity, the present system was successfully applied to estimate the freshness of fish and determine Xa in human urine, which provides potential application in food quality control and clinical analysis. |
| first_indexed | 2025-11-14T08:35:40Z |
| format | Journal Article |
| id | curtin-20.500.11937-34133 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:35:40Z |
| publishDate | 2011 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-341332017-09-13T15:10:07Z A nonenzymatic sensor for xanthine based on electrospun carbon nanofibers modified electrode Tang, X. Liu, Yang Hou, H. You, T. Electrospinning Xanthine Carbon nanofibers Electrocatalytic oxidation Xanthine (Xa) determination is of considerable importance in clinical analysis and food quality control. Therefore, a sensitive nonenzymatic amperometric sensor for Xa based on carbon nanofibers (CNFs) has been proposed. The CNFs, which were prepared by electrospinning technique and subsequent thermal treatment, were used to modify carbon paste electrode (CNF-CPE) to construct the amperometric sensor device without any oxidation pretreatment. In application to Xa electrochemical determination, the CNF-CPE exhibited high electrocatalytic activity and fast amperometric response. Various experimental parameters, such as pH and applied potential were optimized. Under the optimal conditions, the dynamic linear range of Xa was 0.03–21.19M (R = 0.9992) with the detection limit low to 20nM (S/N= 3). With good selectivity and sensitivity, the present system was successfully applied to estimate the freshness of fish and determine Xa in human urine, which provides potential application in food quality control and clinical analysis. 2011 Journal Article http://hdl.handle.net/20.500.11937/34133 10.1016/j.talanta.2010.11.019 Elsevier restricted |
| spellingShingle | Electrospinning Xanthine Carbon nanofibers Electrocatalytic oxidation Tang, X. Liu, Yang Hou, H. You, T. A nonenzymatic sensor for xanthine based on electrospun carbon nanofibers modified electrode |
| title | A nonenzymatic sensor for xanthine based on electrospun carbon nanofibers modified electrode |
| title_full | A nonenzymatic sensor for xanthine based on electrospun carbon nanofibers modified electrode |
| title_fullStr | A nonenzymatic sensor for xanthine based on electrospun carbon nanofibers modified electrode |
| title_full_unstemmed | A nonenzymatic sensor for xanthine based on electrospun carbon nanofibers modified electrode |
| title_short | A nonenzymatic sensor for xanthine based on electrospun carbon nanofibers modified electrode |
| title_sort | nonenzymatic sensor for xanthine based on electrospun carbon nanofibers modified electrode |
| topic | Electrospinning Xanthine Carbon nanofibers Electrocatalytic oxidation |
| url | http://hdl.handle.net/20.500.11937/34133 |