Identification of Inhibitor Binding Site in Human Sirtuin 2 Using Molecular Docking and Dynamics Simulations

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Identification of Inhibitor Binding Site in Human Sirtuin 2 Using Molecular Docking and Dynamics Simulations

The ability to identify the site of a protein that can bind with high affinity to small, drug-like compounds has been an important goal in drug design. Sirtuin 2 (SIRT2), histone deacetylase protein family, plays a central role in the regulation of various pathways. Hence, identification of drug for...

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Bibliographic Details
Main Authors:	Sakkiah, Sugunadevi, Arooj, Mahreen, Rajesh Kumar, Manian, Hyun Eom, Soo, Woo Lee, Keun
Format:	Journal Article
Published:	PLOS 2013
Online Access:	http://hdl.handle.net/20.500.11937/33925

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