Swelling, mechanical strength, and release properties of probucol microcapsules with and without a bile acid, and their potential oral delivery in diabetes

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Swelling, mechanical strength, and release properties of probucol microcapsules with and without a bile acid, and their potential oral delivery in diabetes

We have demonstrated a permeation-enhancing effect of deoxycholic acid (DCA), the bile acid, in diabetic rats. In this study, we designed DCA-based microcapsules for the oral delivery of the antilipidemic drug probucol (PB), which has potential antidiabetic effects. We aimed to further characterize...

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Bibliographic Details
Main Authors:	Negrulj, R., Mooranian, A., Chen-Tan, N., Al-Sallami, H., Mikov, M., Golocorbin-Kon, S., Fakhoury, M., Watts, G., Arfuso, Frank, Al-Salami, H.
Format:	Journal Article
Published:	2015
Online Access:	http://hdl.handle.net/20.500.11937/33899

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