Synthesis of a benzene-annulated analogue of resolving E1 and other lipid mediators

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Synthesis of a benzene-annulated analogue of resolving E1 and other lipid mediators

The resolvins are a class of short-lived, naturally occurring compounds with potent anti-inflammatory effects. Using a sequential Sonogashira-Stille reaction, the formal total synthesis of resolvin E1 and the synthesis of a benzene annulated analogue of this compound were completed. The fusion of th...

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Bibliographic Details
Main Author:	Lombardo, Daniel Mario
Format:	Thesis
Language:	English
Published:	Curtin University 2015
Online Access:	http://hdl.handle.net/20.500.11937/337

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