Synthesis and in vitro evaluation of 1,2,4-triazolo[1,5-a][1,3,5]triazine derivatives as thymidine phosphorylase inhibitors

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Synthesis and in vitro evaluation of 1,2,4-triazolo[1,5-a][1,3,5]triazine derivatives as thymidine phosphorylase inhibitors

In our lead finding program, a series of 1,2,4-triazolo[1,5-a][1,3,5]triazine derivatives were synthesized, and their in vitro thymidine phosphorylase inhibitory potential was explored. Among the different derivatives, compounds having keto group (C = O) at C7 and thioketo group (C = S) at C5 positi...

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Bibliographic Details
Main Authors:	Bera, H., Dolzhenko, Anton, Sun, L., Dutta Gupta, S., Chui, W.
Format:	Journal Article
Published:	2013
Online Access:	http://hdl.handle.net/20.500.11937/33573

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