Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysis
Objective: To determine which simple index of overweight and obesity is the best discriminator of cardiovascular risk factors. Study Design and Setting: This is a meta-analysis of published literature. MEDLINE was searched. Studies that used receiver-operating characteristics (ROC) curve analysis an...
| Main Authors: | , , , |
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| Format: | Journal Article |
| Published: |
Elsevier
2008
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| Online Access: | http://hdl.handle.net/20.500.11937/33307 |
| _version_ | 1848753909381726208 |
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| author | Lee, Crystal Huxley, Rachel Wildman, R. Woodward, M. |
| author_facet | Lee, Crystal Huxley, Rachel Wildman, R. Woodward, M. |
| author_sort | Lee, Crystal |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Objective: To determine which simple index of overweight and obesity is the best discriminator of cardiovascular risk factors. Study Design and Setting: This is a meta-analysis of published literature. MEDLINE was searched. Studies that used receiver-operating characteristics (ROC) curve analysis and published area under the ROC curves (AUC) for overweight and obesity indices with hypertension, type-2 diabetes, and/or dyslipidemia were included. The AUC for each of the four indices, with each risk factor, was pooled using a random-effects model; male and female data were analyzed separately. Results: Ten studies met the inclusion criteria. Body mass index (BMI) was the poorest discriminator for cardiovascular risk factors. Waist-to-height ratio (WHtR) was the best discriminator for hypertension, diabetes, and dyslipidemia in both sexes; its pooled AUC (95% confidence intervals) ranged from 0.67 (0.64, 0.69) to 0.73 (0.70, 0.75) and from 0.68 (0.63, 0.72) to 0.76 (0.70, 0.81) in males and females, respectively. Conclusion: Statistical evidence supports the superiority of measures of centralized obesity, especially WHtR, over BMI, for detecting cardiovascular risk factors in both men and women. © 2008 Elsevier Inc. All rights reserved. |
| first_indexed | 2025-11-14T08:32:00Z |
| format | Journal Article |
| id | curtin-20.500.11937-33307 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:32:00Z |
| publishDate | 2008 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-333072017-09-13T15:31:39Z Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysis Lee, Crystal Huxley, Rachel Wildman, R. Woodward, M. Objective: To determine which simple index of overweight and obesity is the best discriminator of cardiovascular risk factors. Study Design and Setting: This is a meta-analysis of published literature. MEDLINE was searched. Studies that used receiver-operating characteristics (ROC) curve analysis and published area under the ROC curves (AUC) for overweight and obesity indices with hypertension, type-2 diabetes, and/or dyslipidemia were included. The AUC for each of the four indices, with each risk factor, was pooled using a random-effects model; male and female data were analyzed separately. Results: Ten studies met the inclusion criteria. Body mass index (BMI) was the poorest discriminator for cardiovascular risk factors. Waist-to-height ratio (WHtR) was the best discriminator for hypertension, diabetes, and dyslipidemia in both sexes; its pooled AUC (95% confidence intervals) ranged from 0.67 (0.64, 0.69) to 0.73 (0.70, 0.75) and from 0.68 (0.63, 0.72) to 0.76 (0.70, 0.81) in males and females, respectively. Conclusion: Statistical evidence supports the superiority of measures of centralized obesity, especially WHtR, over BMI, for detecting cardiovascular risk factors in both men and women. © 2008 Elsevier Inc. All rights reserved. 2008 Journal Article http://hdl.handle.net/20.500.11937/33307 10.1016/j.jclinepi.2007.08.012 Elsevier restricted |
| spellingShingle | Lee, Crystal Huxley, Rachel Wildman, R. Woodward, M. Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysis |
| title | Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysis |
| title_full | Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysis |
| title_fullStr | Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysis |
| title_full_unstemmed | Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysis |
| title_short | Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysis |
| title_sort | indices of abdominal obesity are better discriminators of cardiovascular risk factors than bmi: a meta-analysis |
| url | http://hdl.handle.net/20.500.11937/33307 |