Probiotic pre-treatment reduces gliclazide permeation (ex vivo) in healthy rats but increases it in diabetic rats to the level seen in untreated healthy rats

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Probiotic pre-treatment reduces gliclazide permeation (ex vivo) in healthy rats but increases it in diabetic rats to the level seen in untreated healthy rats

Aim. To investigate the influence of probiotic pre-treatment on the permeation of the antidiabetic drug gliclazide in healthy and diabetic rats. Methods. Wistar rats (age 2-3 months, weight 350 ± 50 g) were randomly allocated into one of 4 groups (N = 16 each group): healthy control, healthy probiot...

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Bibliographic Details
Main Authors:	Al-Salami, Hani, Butt, G., Tucker, I., Skrbic, R., Golocorbin-Kon, S., Mikov, M.
Format:	Journal Article
Published:	2008
Online Access:	http://hdl.handle.net/20.500.11937/33230

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