Enterocyte Beta Amyloid-Lipoprotein Homeostasis: Implications for Alzheimer's Disease Risk
Alzheimer’s disease beta-amyloid (Aβ) was found in small intestinal enterocytes in association with chylomicrons in wild-type mice. The expression of Aβ was regulated by the availability of substrate from the diet; fasting abolished Aβ, whilst low-fat feeding attenuated Aβ compared to high-fat feedi...
| Main Author: | |
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| Format: | Thesis |
| Language: | English |
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Curtin University
2015
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| Online Access: | http://hdl.handle.net/20.500.11937/330 |
| _version_ | 1848743348083359744 |
|---|---|
| author | Galloway, Susan |
| author_facet | Galloway, Susan |
| author_sort | Galloway, Susan |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Alzheimer’s disease beta-amyloid (Aβ) was found in small intestinal enterocytes in association with chylomicrons in wild-type mice. The expression of Aβ was regulated by the availability of substrate from the diet; fasting abolished Aβ, whilst low-fat feeding attenuated Aβ compared to high-fat feeding. This thesis provides novel point of view in context of dietary fat and in particular saturated fatty acids in modulating AD risk. |
| first_indexed | 2025-11-14T05:44:08Z |
| format | Thesis |
| id | curtin-20.500.11937-330 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T05:44:08Z |
| publishDate | 2015 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-3302017-02-20T06:41:50Z Enterocyte Beta Amyloid-Lipoprotein Homeostasis: Implications for Alzheimer's Disease Risk Galloway, Susan Alzheimer’s disease beta-amyloid (Aβ) was found in small intestinal enterocytes in association with chylomicrons in wild-type mice. The expression of Aβ was regulated by the availability of substrate from the diet; fasting abolished Aβ, whilst low-fat feeding attenuated Aβ compared to high-fat feeding. This thesis provides novel point of view in context of dietary fat and in particular saturated fatty acids in modulating AD risk. 2015 Thesis http://hdl.handle.net/20.500.11937/330 en Curtin University fulltext |
| spellingShingle | Galloway, Susan Enterocyte Beta Amyloid-Lipoprotein Homeostasis: Implications for Alzheimer's Disease Risk |
| title | Enterocyte Beta Amyloid-Lipoprotein Homeostasis: Implications for Alzheimer's Disease Risk |
| title_full | Enterocyte Beta Amyloid-Lipoprotein Homeostasis: Implications for Alzheimer's Disease Risk |
| title_fullStr | Enterocyte Beta Amyloid-Lipoprotein Homeostasis: Implications for Alzheimer's Disease Risk |
| title_full_unstemmed | Enterocyte Beta Amyloid-Lipoprotein Homeostasis: Implications for Alzheimer's Disease Risk |
| title_short | Enterocyte Beta Amyloid-Lipoprotein Homeostasis: Implications for Alzheimer's Disease Risk |
| title_sort | enterocyte beta amyloid-lipoprotein homeostasis: implications for alzheimer's disease risk |
| url | http://hdl.handle.net/20.500.11937/330 |