Unification of Mixing and Cellular Metabolism in Bioreactor Modeling: A Multi-scale Approach
In this paper, we address the progress, challenges and prospect of modeling of mixing in bioreactor. We aim to briefly review the progress in the integration of the mixing behaviors into bioreactor modeling and simulation as well as the obstacles faced towards this integrative modeling effort. Effic...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Conference Paper |
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RSCE-SOMCHE 2008
2008
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/32947 |
| _version_ | 1848753808100818944 |
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| author | Liew, Emily Nandong, Jobrun Samyudia, Yudi |
| author2 | Daud et al. |
| author_facet | Daud et al. Liew, Emily Nandong, Jobrun Samyudia, Yudi |
| author_sort | Liew, Emily |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | In this paper, we address the progress, challenges and prospect of modeling of mixing in bioreactor. We aim to briefly review the progress in the integration of the mixing behaviors into bioreactor modeling and simulation as well as the obstacles faced towards this integrative modeling effort. Efficient operation of bioreactor is crucial in the biotechnological process, not only to ensure good yield but also to maintain the consistent product quality. Process modeling technique has frequently been adopted in the bioreactor design, optimization and control as well as in scale-up process. Transport phenomena problems have generally posed challenging tasks in the bioreactor scale-up. In this respect, the integration of mixing phenomena into the bioreactor modeling is considered as a vital aspect in the design and scale-up of bioreactor. |
| first_indexed | 2025-11-14T08:30:24Z |
| format | Conference Paper |
| id | curtin-20.500.11937-32947 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:30:24Z |
| publishDate | 2008 |
| publisher | RSCE-SOMCHE 2008 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-329472017-01-30T13:34:12Z Unification of Mixing and Cellular Metabolism in Bioreactor Modeling: A Multi-scale Approach Liew, Emily Nandong, Jobrun Samyudia, Yudi Daud et al. multi-scale modeling mixing bioreactor CFD In this paper, we address the progress, challenges and prospect of modeling of mixing in bioreactor. We aim to briefly review the progress in the integration of the mixing behaviors into bioreactor modeling and simulation as well as the obstacles faced towards this integrative modeling effort. Efficient operation of bioreactor is crucial in the biotechnological process, not only to ensure good yield but also to maintain the consistent product quality. Process modeling technique has frequently been adopted in the bioreactor design, optimization and control as well as in scale-up process. Transport phenomena problems have generally posed challenging tasks in the bioreactor scale-up. In this respect, the integration of mixing phenomena into the bioreactor modeling is considered as a vital aspect in the design and scale-up of bioreactor. 2008 Conference Paper http://hdl.handle.net/20.500.11937/32947 RSCE-SOMCHE 2008 fulltext |
| spellingShingle | multi-scale modeling mixing bioreactor CFD Liew, Emily Nandong, Jobrun Samyudia, Yudi Unification of Mixing and Cellular Metabolism in Bioreactor Modeling: A Multi-scale Approach |
| title | Unification of Mixing and Cellular Metabolism in Bioreactor Modeling: A Multi-scale Approach |
| title_full | Unification of Mixing and Cellular Metabolism in Bioreactor Modeling: A Multi-scale Approach |
| title_fullStr | Unification of Mixing and Cellular Metabolism in Bioreactor Modeling: A Multi-scale Approach |
| title_full_unstemmed | Unification of Mixing and Cellular Metabolism in Bioreactor Modeling: A Multi-scale Approach |
| title_short | Unification of Mixing and Cellular Metabolism in Bioreactor Modeling: A Multi-scale Approach |
| title_sort | unification of mixing and cellular metabolism in bioreactor modeling: a multi-scale approach |
| topic | multi-scale modeling mixing bioreactor CFD |
| url | http://hdl.handle.net/20.500.11937/32947 |