Regulatory principles in metabolism -Then and now

QR Code

Regulatory principles in metabolism -Then and now

The importance of metabolic pathways for life and the nature of participating reactions have challenged physiologists and biochemists for over a hundred years. Eric Arthur Newsholme contributed many original hypotheses and concepts to the field of metabolic regulation, demonstrating that metabolic p...

Full description

Bibliographic Details
Main Authors:	Curi, R., Newsholme, P., Marzuca-Nassr, G., Takahashi, H., Hirabara, S., Cruzat, Vinicius, Krause, M., De Bittencourt, P.
Format:	Journal Article
Published:	Portland Press Ltd. 2016
Online Access:	http://hdl.handle.net/20.500.11937/3286

Similar Items

An introduction to glutamine metabolism
by: Cruzat, Vinicius, et al.
Published: (2017)

Glutamine: Metabolism and immune function, supplementation and clinical translation
by: Cruzat, Vinicius, et al.
Published: (2018)

The regulatory roles of NADPH oxidase, intra- and extra-cellular HSP70 in pancreatic islet function, dysfunction and diabetes
by: Krause, M., et al.
Published: (2015)

β-cell metabolism, insulin production and secretion: Metabolic failure resulting in diabetes
by: Chen, Y., et al.
Published: (2016)

Effects of high EPA and high DHA fish oils on changes in signaling associated with protein metabolism induced by hindlimb suspension in rats
by: Marzuca-Nassr, G., et al.
Published: (2016)

The Impact of Inflammation on Pancreatic ß-Cell Metabolism, Function and Failure in T1DM and T2DM: Commonalities and Differences
by: Newsholme, Philip, et al.
Published: (2013)

The chaperone balance hypothesis: The importance of the extracellular to intracellular HSP70 ratio to inflammation-driven type 2 diabetes, the effect of exercise, and the implications for clinical management
by: Krause, M., et al.
Published: (2015)

Amino acid supplementation and impact on immune function in the context of exercise
by: Cruzat, Vinicius, et al.
Published: (2014)

Molecular mechanisms of ROS production and oxidative stress in diabetes
by: Newsholme, Philip, et al.
Published: (2016)

Glutamine and the immune system
by: Cruzat, Vinicius, et al.
Published: (2017)

Activation of Survival and Apoptotic Signaling Pathways in Lymphocytes Exposed to Palmitic Acid
by: Takahashi, H., et al.
Published: (2011)

Molecular Events Linking Oxidative Stress and Inflammation to Insulin Resistance and ß-Cell Dysfunction
by: Keane, Kevin, et al.
Published: (2015)

L-Arginine is essential for pancreatic β-cell functional integrity, metabolism and defense from inflammatory challenge
by: Krause, M., et al.
Published: (2011)

Housekeeping proteins: How useful are they in skeletal muscle diabetes studies and muscle hypertrophy models?
by: Fortes, M., et al.
Published: (2016)

Insulin and IGF-1 receptor autocrine loops are not required for Exendin-4 induced changes to pancreatic ß-cell bioenergetic parameters and metabolism in BRIN-BD11 cells
by: Rowlands, Jordan, et al.
Published: (2018)

GLP-1 receptor signalling promotes β-cell glucose metabolism via mTOR-dependent HIF-1α activation
by: Carlessi, Rodrigo, et al.
Published: (2017)

Oral free and dipeptide forms of glutamine supplementation attenuate oxidative stress and inflammation induced by endotoxemia
by: Cruzat, Vinicius, et al.
Published: (2014)

L-glutamine supplementations enhance liver glutamine-glutathione axis and heat shock factor-1 expression in endurance-exercise trained rats
by: Petry, E., et al.
Published: (2015)

Amino Acid Metabolism
by: Newsholme, Philip, et al.
Published: (2011)

A past and present overview of macrophage metabolism and functional outcomes
by: Curi, R., et al.
Published: (2017)

You, your children, your grandchildren, and their inflammatory responses are what you eat
by: De Bittencourt, P., et al.
Published: (2015)

The fat cell senescence hypothesis: a mechanism responsible for abrogating the resolution of inflammation in chronic disease
by: Newsholme, Philip, et al.
Published: (2014)

Vitamin D Supplementation Does Not Impact Resting Metabolic Rate, Body Composition and Strength in Vitamin D Sufficient Physically Active Adults
by: Romeu Montenegro, Karina, et al.
Published: (2020)

Oral supplementations with free and dipeptide forms of L-glutamine in endotoxemic mice: effects on muscle glutamine-glutathione axis and heat shock proteins
by: Cruzat, Vinicius, et al.
Published: (2014)

Alanyl-glutamine and glutamine plus alanine supplements improve skeletal redox status in trained rats: Involvement of heat shock protein pathways
by: Petry, E., et al.
Published: (2014)

Attenuation of obesity and insulin resistance by fish oil supplementation is associated with improved skeletal muscle mitochondrial function in mice fed a high-fat diet
by: Martins, A., et al.
Published: (2018)

A Novel L-Arginine/L-Glutamine Coupling Hypothesis: Implications for Type 1 Diabetes
by: de Bittencourt Jr, P., et al.
Published: (2011)

Amino acids and diabetes: implications for endocrine, metabolic and immune function
by: Newsholme, Philip, et al.
Published: (2011)

Exercise and possible molecular mechanisms of protection from vascular disease and diabetes: The central role of ROS and nitric oxide
by: Newsholme, Philip, et al.
Published: (2010)

Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic ß-cell line and mouse islets
by: Da Silva Krause, M., et al.
Published: (2012)

Nutrient regulation of insulin secretion and action
by: Newsholme, Philip, et al.
Published: (2014)

Perversion Now!
by: Wright, Colin, et al.
Published: (2017)

Now Showing
by: Elliot, Ron
Published: (2013)

Anyday Now
by: Parfitt, Mark
Published: (2011)

Arachidonic acid actions on functional integrity and attenuation of the negative effects of palmitic acid in a clonal pancreatic ß-cell line
by: Keane, D., et al.
Published: (2011)

The welfare of now and the green (post) politics of the future
by: Catney, P., et al.
Published: (2011)

Why Manifestos, why now?
by: Kent, Michael, et al.
Published: (2018)

The impact of cryopreservation on human peripheral blood leucocyte bioenergetics
by: Keane, Kevin, et al.
Published: (2015)

Pigment epithelium-derived factor (PEDF) regulates metabolism and insulin secretion from a clonal rat pancreatic beta cell line BRIN-BD11 and mouse islets
by: Chen, Y., et al.
Published: (2016)

Now or then ? the clitic - Rru in Panyjima: Temporal properties in discourse
by: Ritz, M., et al.
Published: (2012)