Mechanism-based model of parasite growth and dihydroartemisinin pharmacodynamics in murine malaria

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Mechanism-based model of parasite growth and dihydroartemisinin pharmacodynamics in murine malaria

Murine models are used to study erythrocytic stages of malaria infection, because parasite morphology and development are comparable to those in human malaria infections. Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) models for antimalarials are scarce, despite their potential to optimize...

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Bibliographic Details
Main Authors:	Patel, K., Batty, Kevin, Moore, Brioni, Gibbons, P., Bulitta, J., Kirkpatrick, C.
Format:	Journal Article
Published:	American Society for Microbiology 2013
Online Access:	http://hdl.handle.net/20.500.11937/32716

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