The Emerging Role of PEDF in Stem Cell Biology
Encoded by a single gene, PEDF is a 50 kDa glycoprotein that is highly conserved and is widely expressed among many tissues. Most secreted PEDF deposits within the extracellular matrix, with cell-type-specific functions. While traditionally PEDF is known as a strong antiangiogenic factor, more recen...
| Main Authors: | , , |
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| Format: | Journal Article |
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Hindawi Publishing Corporation
2012
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| Online Access: | http://hdl.handle.net/20.500.11937/32715 |
| _version_ | 1848753740498075648 |
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| author | Elahy, Mina Baindur-Hudson, Swati Dass, Crispin |
| author_facet | Elahy, Mina Baindur-Hudson, Swati Dass, Crispin |
| author_sort | Elahy, Mina |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Encoded by a single gene, PEDF is a 50 kDa glycoprotein that is highly conserved and is widely expressed among many tissues. Most secreted PEDF deposits within the extracellular matrix, with cell-type-specific functions. While traditionally PEDF is known as a strong antiangiogenic factor, more recently, as this paper highlights, PEDF has been linked with stem cell biology, and there is now accumulating evidence demonstrating the effects of PEDF in a variety of stem cells, mainly in supporting stem cell survival and maintaining multipotency. |
| first_indexed | 2025-11-14T08:29:19Z |
| format | Journal Article |
| id | curtin-20.500.11937-32715 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:29:19Z |
| publishDate | 2012 |
| publisher | Hindawi Publishing Corporation |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-327152017-09-13T15:26:24Z The Emerging Role of PEDF in Stem Cell Biology Elahy, Mina Baindur-Hudson, Swati Dass, Crispin Encoded by a single gene, PEDF is a 50 kDa glycoprotein that is highly conserved and is widely expressed among many tissues. Most secreted PEDF deposits within the extracellular matrix, with cell-type-specific functions. While traditionally PEDF is known as a strong antiangiogenic factor, more recently, as this paper highlights, PEDF has been linked with stem cell biology, and there is now accumulating evidence demonstrating the effects of PEDF in a variety of stem cells, mainly in supporting stem cell survival and maintaining multipotency. 2012 Journal Article http://hdl.handle.net/20.500.11937/32715 10.1155/2012/239091 Hindawi Publishing Corporation fulltext |
| spellingShingle | Elahy, Mina Baindur-Hudson, Swati Dass, Crispin The Emerging Role of PEDF in Stem Cell Biology |
| title | The Emerging Role of PEDF in Stem Cell Biology |
| title_full | The Emerging Role of PEDF in Stem Cell Biology |
| title_fullStr | The Emerging Role of PEDF in Stem Cell Biology |
| title_full_unstemmed | The Emerging Role of PEDF in Stem Cell Biology |
| title_short | The Emerging Role of PEDF in Stem Cell Biology |
| title_sort | emerging role of pedf in stem cell biology |
| url | http://hdl.handle.net/20.500.11937/32715 |