Advances in chemistry and biological activity of fluorinated 1,3,5-triazines

QR Code

Advances in chemistry and biological activity of fluorinated 1,3,5-triazines

The substitution of hydrogen by fluorine as bioisosteric replacement has been practised widely in agricultural and medicinal chemistry. This has led to the discovery of many pesticides and therapeutically useful chemical entities. The 1,3,5-triazine heterocycle is found in many biologically active c...

Full description

Bibliographic Details
Main Authors:	Dolzhenko, Anton, Dolzhenko, A., Chui, W.
Other Authors:	Ira V. Gardiner
Format:	Book Chapter
Published:	Nova Science Publishers 2007
Online Access:	http://hdl.handle.net/20.500.11937/32541

Similar Items

Advances in chemistry and biological activity of fluorinated 1,3,5-triazines
by: Dolzhenko, Anton, et al.
Published: (2012)

Pyrazolo[1,5-a][1,3,5]triazines(5-Aza-9-deazapurines): Synthesis and Biological Activity
by: Dolzhenko, Anton, et al.
Published: (2008)

Synthesis and biological activity of fluorinated 7-benzylamino-2-phenyl-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-amines
by: Dolzhenko, Anton, et al.
Published: (2015)

Synthesis and biological activity of fluorinated 7-aryl-2-pyridyl-6,7-dihydro[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-amines.
by: Dolzhenko, Anton, et al.
Published: (2008)

Synthesis of 5,7-Diamino[1,2,4]triazolo[1,2-a][1,3,5]triazines via Annulation of 1,3,5-Triazine Ring onto 3(5)-Amino-1,2,4-trizoles
by: Dolzhenko, Anton, et al.
Published: (2007)

Synthetic Routes towards Thiazolo[1,3,5]triazines (Review)
by: Dolzhenko, Anton
Published: (2011)

Synthesis and structure of 3,4-dihydropyrido[2’,3’:3,4]pyrazolo[1,5-a][1,3,5]triazin-2-amines
by: Dolzhenko, Anton, et al.
Published: (2012)

Synthetic routes towards pyrimido[1,2-a][1,3,5]triazines (Review)
by: Dolzhenko, Anton
Published: (2011)

Synthesis and tautomerism study of 6-benzoylmethyl-1,3,5-triazin-2,4-diamine
by: Sachdeva, N., et al.
Published: (2011)

1,3,5-Triazine-based analogues of purine: From isosteres to privileged scaffolds in medicinal chemistry
by: Lim, Felicia Phei Lin, et al.
Published: (2014)

Practical synthesis of regioisomeric 5(7)-amino-6,7(4,5)-dihydro[1,2,4]triazolo[1,5-a][1,3,5]triazines
by: Dolzhenko, Anton, et al.
Published: (2007)

Synthesis of novel trichloromethyl substituted azolo[1,3,5]triazines
by: Kalinin, D., et al.
Published: (2012)

Synthesis and biological activity of 1,3,5-triazino[1,2-a]benzimidazol-2-amines.
by: Dolzhenko, Anton, et al.
Published: (2007)

Method of obtaining condensed gem-dimethyl substituted amino-1,3,5-triazines
by: Dolzhenko, Anton, et al.
Published: (2007)

7-(4-Fluorobenzylamino)-2-phenyl-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-amine methanol disolvate
by: Dolzhenko, Anton, et al.
Published: (2011)

2-Phenyl-7-(4-pyridylmethylamino)-1,2,4-triazolo[1,5-a][1,3,5]triazin-5(4H)-one
by: Dolzhenko, Anton, et al.
Published: (2011)

4-Amino-substituted pyrazolo[1,5-a][1,3,5]triazin-2-amines: a new practical synthesis and biological activity
by: Lim, Felicia Phei Lin, et al.
Published: (2014)

7,7-Dimethyl-2-phenyl-6,7-dihydro[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-amine.
by: Dolzhenko, Anton, et al.
Published: (2007)

4,4-Dimethyl-3,4-dihydropyrido[2',3':3,4]pyrazolo[1,5-a ][1,3,5]triazin-2-amine ethanol monosolvate
by: Dolzhenko, Anton, et al.
Published: (2011)

4-Phenethylthio-2-phenylpyrazolo[1,5-a][1,3,5]triazin-7(6H)-one
by: Smolnikov, S., et al.
Published: (2017)

7-Dimethylamino-2-phenyl-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-amine methanol solvate.
by: Dolzhenko, Anton, et al.
Published: (2008)

An efficient synthesis of 2,4,7-trisubstituted pyrimido[1,2-a][1,3,5]triazin-6-ones
by: Sachdeva, N., et al.
Published: (2015)

Synthesis and in vitro evaluation of 1,2,4-triazolo[1,5-a][1,3,5]triazine derivatives as thymidine phosphorylase inhibitors
by: Bera, H., et al.
Published: (2013)

Synthesis, anti-thymidine phosphorylase activity and molecular docking of 5-thioxo-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-ones
by: Bera, H., et al.
Published: (2013)

Molecular and Crystal Structure of 7,7-Dimethyl-2-pyridin-4-yl-6,7-dihydro-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-amine [1]
by: Dolzhenko, Anton, et al.
Published: (2011)

Fragment-based approach to the design of 5-chlorouracil-linked-pyrazolo[1, 5-a][1,3,5]triazines as thymidine phosphorylase inhibitors
by: Sun, L., et al.
Published: (2013)

Synthesis, in vitro evaluation of thymidine phosphorylase inhibitory activity, and in silico study of 1,3,5-triazin-2,4-dione and its fused analogues
by: Bera, H., et al.
Published: (2013)

4-Amino-2,8-dimethyl-6H-pyrimido[1,2-a][1,3,5]triazin-6-one
by: Sachdeva, N., et al.
Published: (2010)

2-Amino-4-(4-bromophenyl)-8-trifluoromethyl-3,4-dihydropyrimido[1,2-a][1,3,5]triazin-6(5H)-one
by: Dolzhenko, Anton, et al.
Published: (2009)

One-pot multicomponent synthesis of bis(diamino-1,3,5-triazines) under microwave irradiation.
by: Muhammad Syafiq, Sahari, et al.
Published: (2022)

Regioselective synthesis of pyrimido [1,2-a][1,3,5]triazin-6-ones via reaction of 1-(6-oxo-1,6-dihydropyrimidin-2-yl)guanidines with triethylorthoacetate: Observation of an unexpected rearrangement
by: Sachdeva, N., et al.
Published: (2012)

A new synthesis of amino substituted azolo[1,3,5]triazines via reaction of N1,N1-dimethyl-N2-azolylformamidines with cyanamide
by: Kalinin, D., et al.
Published: (2013)

A structure-activity relationship study of 1,2,4-triazolo[1,5-a][1,3,5] triazin-5,7-dione and its 5-thioxo analogues on anti-thymidine phosphorylase and associated anti-angiogenic activities
by: Bera, H., et al.
Published: (2013)

A one-pot, three-component, microwave-promoted synthesis of 2-amino-substituted 7-amino-1,2,4-triazolo[1,5-a][1,3,5]triazines
by: Kalinina, S., et al.
Published: (2013)

Simple synthesis of 2-amino-4-(het)aryl-4,6-dihydro-1(3)(11)H-[1,3,5]triazino[2,1-b]quinazolin-6-ones
by: Dolzhenko, Anton, et al.
Published: (2008)

A one-pot, three-component, microwave-assisted synthesis of novel 7-amino-substituted 4-aminopyrazolo[1,5-a][1,3,5]triazine-8-carbonitriles
by: Lim, F., et al.
Published: (2015)

Crystal structure of 7-(4-methylphenyl)imidazo[1,2-a][1,3,5]triazin-4-amine, C12H11N5
by: Lim, F., et al.
Published: (2018)

New One-Pot Synthesis of 1,3,5-Triazines: Three-Component Condensation, Dimroth Rearrangement, and Dehydrogenative Aromatization
by: Ahmad Junaid,, et al.
Published: (2019)

A one-pot, multicomponent reaction for the synthesis of novel 2-alkyl substituted 4-aminoimidazo[1,2-: A] [1,3,5]triazines
by: Lim, F., et al.
Published: (2018)

A synthesis of new 7-amino-substituted 4-aminopyrazolo[1,5-a][1,3,5]triazines via a selective three-component triazine ring annulation
by: Lim, Felicia Phei Lin, et al.
Published: (2019)

Cannot write session to /tmp/vufind_sessions/sess_nl801894j1mluc2cgnp6ge12c4