Electrochemical Synthesis, Characterisation, and Preliminary Biological Evaluation of an Anodic Aluminium Oxide Membrane with a pore size of 100 nanometres for a Potential Cell Culture Substrate
In this study we investigate the electrochemical synthesis and characterisation of a nanometre scale porous anodic aluminium oxide (AAO) membranes with a mean pore diameter of 100 nm. The membranes exhibit interesting properties such as controllable pore diameters, periodicity and density distributi...
| Main Authors: | , , , , |
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| Format: | Journal Article |
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Scientific & Academic Publishing
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/32349 |
| _version_ | 1848753638492602368 |
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| author | Poinern, Gerrard Le, Xuan Hager, Marilyn Becker, Thomas Fawcett, Derek |
| author_facet | Poinern, Gerrard Le, Xuan Hager, Marilyn Becker, Thomas Fawcett, Derek |
| author_sort | Poinern, Gerrard |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | In this study we investigate the electrochemical synthesis and characterisation of a nanometre scale porous anodic aluminium oxide (AAO) membranes with a mean pore diameter of 100 nm. The membranes exhibit interesting properties such as controllable pore diameters, periodicity and density distribution. These properties can be preselected by adjusting the controlling parameters of a temperature controlled two-step anodization process. The surface features of the nanometre scale membrane such as pore density, pore diameter and inter-pore distance were quantified using field emission scanning electron microscopy (FESEM) and atomic force microscopy (AFM). A preliminary biological evaluation of the membranes was carried out to determine cell adhesion and morphology using the Cercopithecus aethiops[African green monkey – (Vero)] kidney epithelial cell line. Optical microscopy, FESEM and AFM investigations revealed the presence of focal adhesion sites over the surface of the porous membranes. The positive outcomes of the study, indicates that AAO membranes can be used as a viable tissue scaffold for potential tissue engineering applications in the future. |
| first_indexed | 2025-11-14T08:27:42Z |
| format | Journal Article |
| id | curtin-20.500.11937-32349 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:27:42Z |
| publishDate | 2013 |
| publisher | Scientific & Academic Publishing |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-323492017-09-13T15:23:29Z Electrochemical Synthesis, Characterisation, and Preliminary Biological Evaluation of an Anodic Aluminium Oxide Membrane with a pore size of 100 nanometres for a Potential Cell Culture Substrate Poinern, Gerrard Le, Xuan Hager, Marilyn Becker, Thomas Fawcett, Derek Tissue Scaffold Regenerative Tissues Nano-porous Anodic Aluminium Oxide Cell Substrate In this study we investigate the electrochemical synthesis and characterisation of a nanometre scale porous anodic aluminium oxide (AAO) membranes with a mean pore diameter of 100 nm. The membranes exhibit interesting properties such as controllable pore diameters, periodicity and density distribution. These properties can be preselected by adjusting the controlling parameters of a temperature controlled two-step anodization process. The surface features of the nanometre scale membrane such as pore density, pore diameter and inter-pore distance were quantified using field emission scanning electron microscopy (FESEM) and atomic force microscopy (AFM). A preliminary biological evaluation of the membranes was carried out to determine cell adhesion and morphology using the Cercopithecus aethiops[African green monkey – (Vero)] kidney epithelial cell line. Optical microscopy, FESEM and AFM investigations revealed the presence of focal adhesion sites over the surface of the porous membranes. The positive outcomes of the study, indicates that AAO membranes can be used as a viable tissue scaffold for potential tissue engineering applications in the future. 2013 Journal Article http://hdl.handle.net/20.500.11937/32349 10.5923/j.ajbe.20130306.01 Scientific & Academic Publishing restricted |
| spellingShingle | Tissue Scaffold Regenerative Tissues Nano-porous Anodic Aluminium Oxide Cell Substrate Poinern, Gerrard Le, Xuan Hager, Marilyn Becker, Thomas Fawcett, Derek Electrochemical Synthesis, Characterisation, and Preliminary Biological Evaluation of an Anodic Aluminium Oxide Membrane with a pore size of 100 nanometres for a Potential Cell Culture Substrate |
| title | Electrochemical Synthesis, Characterisation, and Preliminary Biological Evaluation of an Anodic Aluminium Oxide Membrane with a pore size of 100 nanometres for a Potential Cell Culture Substrate |
| title_full | Electrochemical Synthesis, Characterisation, and Preliminary Biological Evaluation of an Anodic Aluminium Oxide Membrane with a pore size of 100 nanometres for a Potential Cell Culture Substrate |
| title_fullStr | Electrochemical Synthesis, Characterisation, and Preliminary Biological Evaluation of an Anodic Aluminium Oxide Membrane with a pore size of 100 nanometres for a Potential Cell Culture Substrate |
| title_full_unstemmed | Electrochemical Synthesis, Characterisation, and Preliminary Biological Evaluation of an Anodic Aluminium Oxide Membrane with a pore size of 100 nanometres for a Potential Cell Culture Substrate |
| title_short | Electrochemical Synthesis, Characterisation, and Preliminary Biological Evaluation of an Anodic Aluminium Oxide Membrane with a pore size of 100 nanometres for a Potential Cell Culture Substrate |
| title_sort | electrochemical synthesis, characterisation, and preliminary biological evaluation of an anodic aluminium oxide membrane with a pore size of 100 nanometres for a potential cell culture substrate |
| topic | Tissue Scaffold Regenerative Tissues Nano-porous Anodic Aluminium Oxide Cell Substrate |
| url | http://hdl.handle.net/20.500.11937/32349 |