Aromatic Cation Activation: Nucleophilic Substitution of Alcohols and Carboxylic Acids
A new method for the nucleophilic substitution of alcohols and carboxylic acids using aromatic tropyliumcation activation has been developed. This article reports the use of chloro tropylium chloride for the rapid generation of alkyl halides and acyl chlorides under very mild reaction conditions. It...
| Main Authors: | , |
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| Format: | Journal Article |
| Published: |
American Chemical Society
2014
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| Online Access: | http://hdl.handle.net/20.500.11937/32003 |
| _version_ | 1848753541067309056 |
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| author | Nguyen, Thanh Vinh Bekensir, Alp |
| author_facet | Nguyen, Thanh Vinh Bekensir, Alp |
| author_sort | Nguyen, Thanh Vinh |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | A new method for the nucleophilic substitution of alcohols and carboxylic acids using aromatic tropyliumcation activation has been developed. This article reports the use of chloro tropylium chloride for the rapid generation of alkyl halides and acyl chlorides under very mild reaction conditions. It demonstrates, for the first time, the synthetic potential of tropylium cations in promoting chemical transformations. |
| first_indexed | 2025-11-14T08:26:09Z |
| format | Journal Article |
| id | curtin-20.500.11937-32003 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:26:09Z |
| publishDate | 2014 |
| publisher | American Chemical Society |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-320032017-09-13T15:17:40Z Aromatic Cation Activation: Nucleophilic Substitution of Alcohols and Carboxylic Acids Nguyen, Thanh Vinh Bekensir, Alp A new method for the nucleophilic substitution of alcohols and carboxylic acids using aromatic tropyliumcation activation has been developed. This article reports the use of chloro tropylium chloride for the rapid generation of alkyl halides and acyl chlorides under very mild reaction conditions. It demonstrates, for the first time, the synthetic potential of tropylium cations in promoting chemical transformations. 2014 Journal Article http://hdl.handle.net/20.500.11937/32003 10.1021/ol5003972 American Chemical Society restricted |
| spellingShingle | Nguyen, Thanh Vinh Bekensir, Alp Aromatic Cation Activation: Nucleophilic Substitution of Alcohols and Carboxylic Acids |
| title | Aromatic Cation Activation: Nucleophilic Substitution of Alcohols and Carboxylic Acids |
| title_full | Aromatic Cation Activation: Nucleophilic Substitution of Alcohols and Carboxylic Acids |
| title_fullStr | Aromatic Cation Activation: Nucleophilic Substitution of Alcohols and Carboxylic Acids |
| title_full_unstemmed | Aromatic Cation Activation: Nucleophilic Substitution of Alcohols and Carboxylic Acids |
| title_short | Aromatic Cation Activation: Nucleophilic Substitution of Alcohols and Carboxylic Acids |
| title_sort | aromatic cation activation: nucleophilic substitution of alcohols and carboxylic acids |
| url | http://hdl.handle.net/20.500.11937/32003 |