Multislice CT angiography in the assessment of coronary artery in-stent restenosis: A systematic review.
Purpose: The aim of this study was to perform a systematic review of the diagnostic accuracy of multi-detector row computed tomography angiography (MDCT) for detection of coronary in-stent restenosis in patients treated with coronary stenting when compared to invasive catheter angiography.Materials...
| Main Authors: | , , |
|---|---|
| Format: | Journal Article |
| Published: |
Elsevier
2008
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/3193 |
| _version_ | 1848744164402921472 |
|---|---|
| author | Sun, Zhonghua Davidson, R. Lin, C. |
| author_facet | Sun, Zhonghua Davidson, R. Lin, C. |
| author_sort | Sun, Zhonghua |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Purpose: The aim of this study was to perform a systematic review of the diagnostic accuracy of multi-detector row computed tomography angiography (MDCT) for detection of coronary in-stent restenosis in patients treated with coronary stenting when compared to invasive catheter angiography.Materials and Methods: A search of PUBMED and MEDLINE databases for English literature was performed. Only studies with at least 10 patients comparing 16- or more detector rows MDCT angiography with invasive catheter angiography in the detection of coronary in-stent restenosis (more than 50% stenosis) were included for analysis. Sensitivity and specificity estimates pooled across studies were tested using a fixed effects model.Results: 15 studies met selection criteria for inclusion in the analysis. There were eight studies performed with 16-detector row CT scanners, and five studies with 64-detector row scanners and one study with a 40-detector scanner. The remaining study was performed with a mixture of 16-and 64-detector row scanners. Prevalence of in-stent restenosis following coronary stenting was 18% (95% CI: 13%, 24%). Pooled estimates of the sensitivity and specificity of overall MDCT angiography for the detection of coronary in-stent restenosis was 85% (95% CI: 78%, 90%) and 97% (95% CI: 95%, 98%), respectively. No significant difference was found between 16- and 64-detector row scanners regarding the sensitivity and specificity of MDCT for assessment of in-stent restenosis (p>0.05).Conclusion: The results showed that MDCT angiography (with 16 or more detector rows) has moderate sensitivity and high specificity for the detection of coronary in-stent restenosis when compared to invasive catheter angiography. A high specificity value of MDCT may be most valuable as a non-invasive technique of excluding coronary stent restenosis or occlusion. The main factors affecting visualization are stent diameters and stent materials. |
| first_indexed | 2025-11-14T05:57:07Z |
| format | Journal Article |
| id | curtin-20.500.11937-3193 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T05:57:07Z |
| publishDate | 2008 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-31932018-09-11T02:00:54Z Multislice CT angiography in the assessment of coronary artery in-stent restenosis: A systematic review. Sun, Zhonghua Davidson, R. Lin, C. coronary artery disease Multi-detector computed tomography restenosis stent artifacts Purpose: The aim of this study was to perform a systematic review of the diagnostic accuracy of multi-detector row computed tomography angiography (MDCT) for detection of coronary in-stent restenosis in patients treated with coronary stenting when compared to invasive catheter angiography.Materials and Methods: A search of PUBMED and MEDLINE databases for English literature was performed. Only studies with at least 10 patients comparing 16- or more detector rows MDCT angiography with invasive catheter angiography in the detection of coronary in-stent restenosis (more than 50% stenosis) were included for analysis. Sensitivity and specificity estimates pooled across studies were tested using a fixed effects model.Results: 15 studies met selection criteria for inclusion in the analysis. There were eight studies performed with 16-detector row CT scanners, and five studies with 64-detector row scanners and one study with a 40-detector scanner. The remaining study was performed with a mixture of 16-and 64-detector row scanners. Prevalence of in-stent restenosis following coronary stenting was 18% (95% CI: 13%, 24%). Pooled estimates of the sensitivity and specificity of overall MDCT angiography for the detection of coronary in-stent restenosis was 85% (95% CI: 78%, 90%) and 97% (95% CI: 95%, 98%), respectively. No significant difference was found between 16- and 64-detector row scanners regarding the sensitivity and specificity of MDCT for assessment of in-stent restenosis (p>0.05).Conclusion: The results showed that MDCT angiography (with 16 or more detector rows) has moderate sensitivity and high specificity for the detection of coronary in-stent restenosis when compared to invasive catheter angiography. A high specificity value of MDCT may be most valuable as a non-invasive technique of excluding coronary stent restenosis or occlusion. The main factors affecting visualization are stent diameters and stent materials. 2008 Journal Article http://hdl.handle.net/20.500.11937/3193 10.1016/j.ejrad.2007.11.030 Elsevier fulltext |
| spellingShingle | coronary artery disease Multi-detector computed tomography restenosis stent artifacts Sun, Zhonghua Davidson, R. Lin, C. Multislice CT angiography in the assessment of coronary artery in-stent restenosis: A systematic review. |
| title | Multislice CT angiography in the assessment of coronary artery in-stent restenosis: A systematic review. |
| title_full | Multislice CT angiography in the assessment of coronary artery in-stent restenosis: A systematic review. |
| title_fullStr | Multislice CT angiography in the assessment of coronary artery in-stent restenosis: A systematic review. |
| title_full_unstemmed | Multislice CT angiography in the assessment of coronary artery in-stent restenosis: A systematic review. |
| title_short | Multislice CT angiography in the assessment of coronary artery in-stent restenosis: A systematic review. |
| title_sort | multislice ct angiography in the assessment of coronary artery in-stent restenosis: a systematic review. |
| topic | coronary artery disease Multi-detector computed tomography restenosis stent artifacts |
| url | http://hdl.handle.net/20.500.11937/3193 |