Cost-Effectiveness of an Advance Notification Letter to Increase Colorectal Cancer Screening

Objectives: The aim of this study is to evaluate the cost-effectiveness of a patient-direct mailed advance notification letter on participants of a National Bowel Cancer Screening Program (NBCSP) in Australia, which was launched in August 2006 and offers free fecal occult blood testing to all Austra...

Full description

Bibliographic Details
Main Authors: Cronin, P., Goodall, S., O'Keefe, C., Lockett, T., Norman, Richard, Church, J.
Format: Journal Article
Published: Cambridge University Press 2013
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/3191
_version_ 1848744163825156096
author Cronin, P.
Goodall, S.
O'Keefe, C.
Lockett, T.
Norman, Richard
Church, J.
author_facet Cronin, P.
Goodall, S.
O'Keefe, C.
Lockett, T.
Norman, Richard
Church, J.
author_sort Cronin, P.
building Curtin Institutional Repository
collection Online Access
description Objectives: The aim of this study is to evaluate the cost-effectiveness of a patient-direct mailed advance notification letter on participants of a National Bowel Cancer Screening Program (NBCSP) in Australia, which was launched in August 2006 and offers free fecal occult blood testing to all Australians turning 50, 55, or 65 years of age in any given year.Methods: This study followed a hypothetical cohort of 50-year-old, 55-year-old, and 65-year-old patients undergoing fecal occult blood test (FOBT) screening through a decision analytic Markov model. The intervention compared two strategies: (i) advance letter, NBCSP, and FOBT compared with (ii) NBCSP and FOBT. The main outcome measures were life-years gained (LYG), quality-adjusted life-years (QALYs) gained and incremental cost-effectiveness ratio.Results: An advance notification screening letter would yield an additional 54 per 100,000 colorectal cancer deaths avoided compared with no letter. The estimated cost-effectiveness was $3,976 per LYG and $6,976 per QALY gained.Conclusions: An advance notification letter in the NBCSP may have a significant impact on LYG and cancer deaths avoided. It is cost-effective and offers a feasible strategy that could be rolled out across other screening program at an acceptable cost.
first_indexed 2025-11-14T05:57:06Z
format Journal Article
id curtin-20.500.11937-3191
institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T05:57:06Z
publishDate 2013
publisher Cambridge University Press
recordtype eprints
repository_type Digital Repository
spelling curtin-20.500.11937-31912017-09-13T14:45:11Z Cost-Effectiveness of an Advance Notification Letter to Increase Colorectal Cancer Screening Cronin, P. Goodall, S. O'Keefe, C. Lockett, T. Norman, Richard Church, J. Screening Cost-effectiveness analysis Colorectal cancer Objectives: The aim of this study is to evaluate the cost-effectiveness of a patient-direct mailed advance notification letter on participants of a National Bowel Cancer Screening Program (NBCSP) in Australia, which was launched in August 2006 and offers free fecal occult blood testing to all Australians turning 50, 55, or 65 years of age in any given year.Methods: This study followed a hypothetical cohort of 50-year-old, 55-year-old, and 65-year-old patients undergoing fecal occult blood test (FOBT) screening through a decision analytic Markov model. The intervention compared two strategies: (i) advance letter, NBCSP, and FOBT compared with (ii) NBCSP and FOBT. The main outcome measures were life-years gained (LYG), quality-adjusted life-years (QALYs) gained and incremental cost-effectiveness ratio.Results: An advance notification screening letter would yield an additional 54 per 100,000 colorectal cancer deaths avoided compared with no letter. The estimated cost-effectiveness was $3,976 per LYG and $6,976 per QALY gained.Conclusions: An advance notification letter in the NBCSP may have a significant impact on LYG and cancer deaths avoided. It is cost-effective and offers a feasible strategy that could be rolled out across other screening program at an acceptable cost. 2013 Journal Article http://hdl.handle.net/20.500.11937/3191 10.1017/S0266462313000226 Cambridge University Press restricted
spellingShingle Screening
Cost-effectiveness analysis
Colorectal cancer
Cronin, P.
Goodall, S.
O'Keefe, C.
Lockett, T.
Norman, Richard
Church, J.
Cost-Effectiveness of an Advance Notification Letter to Increase Colorectal Cancer Screening
title Cost-Effectiveness of an Advance Notification Letter to Increase Colorectal Cancer Screening
title_full Cost-Effectiveness of an Advance Notification Letter to Increase Colorectal Cancer Screening
title_fullStr Cost-Effectiveness of an Advance Notification Letter to Increase Colorectal Cancer Screening
title_full_unstemmed Cost-Effectiveness of an Advance Notification Letter to Increase Colorectal Cancer Screening
title_short Cost-Effectiveness of an Advance Notification Letter to Increase Colorectal Cancer Screening
title_sort cost-effectiveness of an advance notification letter to increase colorectal cancer screening
topic Screening
Cost-effectiveness analysis
Colorectal cancer
url http://hdl.handle.net/20.500.11937/3191