Mutation of FOXL2 in granulosa-cell tumors of the ovary

Mutation of FOXL2 in granulosa-cell tumors of the ovary

BACKGROUND: Granulosa-cell tumors (GCTs) are the most common type of malignant ovarian sex cord-stromal tumor (SCST). The pathogenesis of these tumors is unknown. Moreover, their histopathological diagnosis can be challenging, and there is no curative treatment beyond surgery. METHODS: We analyzed f...

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Main Authors: Shah, S., Köbel, M., Senz, J., Morin, R., Clarke, B., Wiegand, K., Leung, G., Zayed, A., Mehl, E., Kalloger, S., Sun, M., Giuliany, R., Yorida, E., Jones, S., Varhol, Richard, Swenerton, K., Miller, D., Clement, P., Crane, C., Madore, J., Provencher, D., Leung, P., DeFazio, A., Khattra, J., Turashvili, G., Zhao, Y., Zeng, T., Glover, J., Vanderhyden, B., Zhao, C., Parkinson, C., Jimenez-Linan, M., Bowtell, D., Mes-Masson, A., Brenton, J., Aparicio, S., Boyd, N., Hirst, M., Gilks, C., Marra, M., Huntsman, D.
Format: Journal Article
Published: Massachusetts Medical Society 2009
Online Access:http://hdl.handle.net/20.500.11937/31863

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