Formal infectious diseases consultation is associated with decreased mortality in Staphylococcus aureus bacteraemia

To determine the impact of infectious diseases consultation (IDC) in Staphylococcus aureus bacteraemia. All MRSA bacteraemia and a random subset of MSSA bacteraemia were retrospectively analysed. Out of 599 SAB episodes, 162 (27%) were followed by an IDC. Patients with IDC were younger and more freq...

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Main Authors: Robinson, J., Pozzi-Langhi, S., Phillips, M., Pearson, J., Christiansen, K., Coombs, Geoffrey, Murray, R.
Format: Journal Article
Published: Springer 2012
Online Access:http://hdl.handle.net/20.500.11937/31672
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author Robinson, J.
Pozzi-Langhi, S.
Phillips, M.
Pearson, J.
Christiansen, K.
Coombs, Geoffrey
Murray, R.
author_facet Robinson, J.
Pozzi-Langhi, S.
Phillips, M.
Pearson, J.
Christiansen, K.
Coombs, Geoffrey
Murray, R.
author_sort Robinson, J.
building Curtin Institutional Repository
collection Online Access
description To determine the impact of infectious diseases consultation (IDC) in Staphylococcus aureus bacteraemia. All MRSA bacteraemia and a random subset of MSSA bacteraemia were retrospectively analysed. Out of 599 SAB episodes, 162 (27%) were followed by an IDC. Patients with IDC were younger and more frequently intravenous drug users, but fewer resided in a long-term care facility or were indigenous. Hospital length of stay was longer (29.5 vs 17 days, p < 0.001), and endocarditis (19.1% vs 7.3%, p < 0.001) and metastatic seeding (22.2% vs 10.1%, p < 0.001) were more frequent in the IDC group; however, SAPS II scores were lower in the IDC group (27 vs 37, p < 0.001). ICU admission rates in the two groups were similar. The isolate tested susceptible to empirical therapy more frequently in the IDC group (88.9% vs 78.0%, p = 0.003). Seven-day (3.1 vs 16.5%), 30-day (8.0% vs 27.0%) and 1-year mortality (22.2% vs 44.9%) were all lower in the IDC group (all p < 0.001). Multivariate analysis showed that effective initial therapy was the only variable associated with the protective effect of IDC. In patients with SAB, all-cause mortality was significantly lower in patients who had an IDC, because of the higher proportion of patients receiving effective initial antibiotics.
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spelling curtin-20.500.11937-316722017-09-13T15:33:38Z Formal infectious diseases consultation is associated with decreased mortality in Staphylococcus aureus bacteraemia Robinson, J. Pozzi-Langhi, S. Phillips, M. Pearson, J. Christiansen, K. Coombs, Geoffrey Murray, R. To determine the impact of infectious diseases consultation (IDC) in Staphylococcus aureus bacteraemia. All MRSA bacteraemia and a random subset of MSSA bacteraemia were retrospectively analysed. Out of 599 SAB episodes, 162 (27%) were followed by an IDC. Patients with IDC were younger and more frequently intravenous drug users, but fewer resided in a long-term care facility or were indigenous. Hospital length of stay was longer (29.5 vs 17 days, p < 0.001), and endocarditis (19.1% vs 7.3%, p < 0.001) and metastatic seeding (22.2% vs 10.1%, p < 0.001) were more frequent in the IDC group; however, SAPS II scores were lower in the IDC group (27 vs 37, p < 0.001). ICU admission rates in the two groups were similar. The isolate tested susceptible to empirical therapy more frequently in the IDC group (88.9% vs 78.0%, p = 0.003). Seven-day (3.1 vs 16.5%), 30-day (8.0% vs 27.0%) and 1-year mortality (22.2% vs 44.9%) were all lower in the IDC group (all p < 0.001). Multivariate analysis showed that effective initial therapy was the only variable associated with the protective effect of IDC. In patients with SAB, all-cause mortality was significantly lower in patients who had an IDC, because of the higher proportion of patients receiving effective initial antibiotics. 2012 Journal Article http://hdl.handle.net/20.500.11937/31672 10.1007/s10096-012-1585-y Springer restricted
spellingShingle Robinson, J.
Pozzi-Langhi, S.
Phillips, M.
Pearson, J.
Christiansen, K.
Coombs, Geoffrey
Murray, R.
Formal infectious diseases consultation is associated with decreased mortality in Staphylococcus aureus bacteraemia
title Formal infectious diseases consultation is associated with decreased mortality in Staphylococcus aureus bacteraemia
title_full Formal infectious diseases consultation is associated with decreased mortality in Staphylococcus aureus bacteraemia
title_fullStr Formal infectious diseases consultation is associated with decreased mortality in Staphylococcus aureus bacteraemia
title_full_unstemmed Formal infectious diseases consultation is associated with decreased mortality in Staphylococcus aureus bacteraemia
title_short Formal infectious diseases consultation is associated with decreased mortality in Staphylococcus aureus bacteraemia
title_sort formal infectious diseases consultation is associated with decreased mortality in staphylococcus aureus bacteraemia
url http://hdl.handle.net/20.500.11937/31672