Pigment epithelium-derived factor as a natural matrix metalloproteinase inhibitor: a comparison with classical matrix metalloproteinase inhibitors used for cancer treatment

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Pigment epithelium-derived factor as a natural matrix metalloproteinase inhibitor: a comparison with classical matrix metalloproteinase inhibitors used for cancer treatment

Objectives: In the 1990s, the discovery of the important role of matrix metalloproteinases (MMPs) in cancer angiogenesis, growth and metastasis galvanised research efforts to search for ways to inhibit these MMPs. To date, this has resulted in the investigation of approximately 50 MMPIs which have u...

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Bibliographic Details
Main Authors:	Alcantara, M., Dass, Crispin
Format:	Journal Article
Published:	John Wiley & Sons Ltd. 2014
Subjects:	pigment epithelium-derived factor metastasis matrix metalloproteinase inhibitor angiogenesis matrix metalloproteinase
Online Access:	http://hdl.handle.net/20.500.11937/3164

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