Parental Occupational Exposure to Engine Exhausts and Childhood Brain Tumors
Childhood brain tumors (CBT) are the leading cause of cancer death in children; their risk factors are still largely unknown. Since most CBTs are diagnosed before five years of age, prenatal exposure and early postnatal factors may be involved in their etiology. We investigated the association betwe...
| Main Authors: | , , , , , , , , |
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| Format: | Journal Article |
| Published: |
John Wiley & Sons, Inc.
2013
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/31560 |
| _version_ | 1848753414084755456 |
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| author | Peters, S. Glass, D. Reid, Alison de Klerk, N. Armstrong, B. Kellie, S. Ashton, L. Milne, Elizabeth Fritschi, Lin |
| author_facet | Peters, S. Glass, D. Reid, Alison de Klerk, N. Armstrong, B. Kellie, S. Ashton, L. Milne, Elizabeth Fritschi, Lin |
| author_sort | Peters, S. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Childhood brain tumors (CBT) are the leading cause of cancer death in children; their risk factors are still largely unknown. Since most CBTs are diagnosed before five years of age, prenatal exposure and early postnatal factors may be involved in their etiology. We investigated the association between CBT and parental occupational exposure to engine exhausts in an Australian population-based case–control study. Parents of 306 cases and 950 controls completed detailed occupational histories. Odds ratios (OR) and 95% confidence intervals (CI) were estimated for both maternal and paternal exposure in keytime periods. Increased risks were observed for maternal exposure to diesel exhaust any time before the child’s birth (OR 2.03, 95% CI 1.09–3.81) and paternal exposure around the time of the child’s conception (OR 1.62, 95% CI 1.12–2.34). No clear associations with other engine exhausts were found. Our results suggest that parental occupational exposure to diesel exhaust may increase the risk of CBT. |
| first_indexed | 2025-11-14T08:24:08Z |
| format | Journal Article |
| id | curtin-20.500.11937-31560 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:24:08Z |
| publishDate | 2013 |
| publisher | John Wiley & Sons, Inc. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-315602019-02-19T04:27:57Z Parental Occupational Exposure to Engine Exhausts and Childhood Brain Tumors Peters, S. Glass, D. Reid, Alison de Klerk, N. Armstrong, B. Kellie, S. Ashton, L. Milne, Elizabeth Fritschi, Lin parental exposure childhood cancer case–control study diesel exhaust Childhood brain tumors (CBT) are the leading cause of cancer death in children; their risk factors are still largely unknown. Since most CBTs are diagnosed before five years of age, prenatal exposure and early postnatal factors may be involved in their etiology. We investigated the association between CBT and parental occupational exposure to engine exhausts in an Australian population-based case–control study. Parents of 306 cases and 950 controls completed detailed occupational histories. Odds ratios (OR) and 95% confidence intervals (CI) were estimated for both maternal and paternal exposure in keytime periods. Increased risks were observed for maternal exposure to diesel exhaust any time before the child’s birth (OR 2.03, 95% CI 1.09–3.81) and paternal exposure around the time of the child’s conception (OR 1.62, 95% CI 1.12–2.34). No clear associations with other engine exhausts were found. Our results suggest that parental occupational exposure to diesel exhaust may increase the risk of CBT. 2013 Journal Article http://hdl.handle.net/20.500.11937/31560 John Wiley & Sons, Inc. restricted |
| spellingShingle | parental exposure childhood cancer case–control study diesel exhaust Peters, S. Glass, D. Reid, Alison de Klerk, N. Armstrong, B. Kellie, S. Ashton, L. Milne, Elizabeth Fritschi, Lin Parental Occupational Exposure to Engine Exhausts and Childhood Brain Tumors |
| title | Parental Occupational Exposure to Engine Exhausts and Childhood Brain Tumors |
| title_full | Parental Occupational Exposure to Engine Exhausts and Childhood Brain Tumors |
| title_fullStr | Parental Occupational Exposure to Engine Exhausts and Childhood Brain Tumors |
| title_full_unstemmed | Parental Occupational Exposure to Engine Exhausts and Childhood Brain Tumors |
| title_short | Parental Occupational Exposure to Engine Exhausts and Childhood Brain Tumors |
| title_sort | parental occupational exposure to engine exhausts and childhood brain tumors |
| topic | parental exposure childhood cancer case–control study diesel exhaust |
| url | http://hdl.handle.net/20.500.11937/31560 |