Synthesis and structure of 3,4-dihydropyrido[2’,3’:3,4]pyrazolo[1,5-a][1,3,5]triazin-2-amines
A new convenient synthon for heterocyclic chemistry, namely 1H-pyrazolo[3,4-b]pyridin-3-ylguanidine was successfully prepared by selective guanylation of 1H-pyrazolo[3,4-b]pyridin-3-amine. A series of 3,4-dihydropyrido[2′,3′:3,4]pyrazolo[1,5-a][1,3,5]triazin-2-amines was synthesized from 1H-pyrazolo...
| Main Authors: | , , , |
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| Format: | Journal Article |
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John Wiley & Sons
2012
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| Online Access: | http://hdl.handle.net/20.500.11937/3152 |
| _version_ | 1848744153100320768 |
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| author | Dolzhenko, Anton Bai, S. Dolzhenko, A. Chui, W. |
| author_facet | Dolzhenko, Anton Bai, S. Dolzhenko, A. Chui, W. |
| author_sort | Dolzhenko, Anton |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | A new convenient synthon for heterocyclic chemistry, namely 1H-pyrazolo[3,4-b]pyridin-3-ylguanidine was successfully prepared by selective guanylation of 1H-pyrazolo[3,4-b]pyridin-3-amine. A series of 3,4-dihydropyrido[2′,3′:3,4]pyrazolo[1,5-a][1,3,5]triazin-2-amines was synthesized from 1H-pyrazolo[3,4-b]pyridin-3-ylguanidine using aldehydes or ketones as one-carbon inserting reagents. The tautomeric preferences of the products were determined using spectroscopic (e.g., 2D NOESY NMR) and single crystal X-ray diffraction data. |
| first_indexed | 2025-11-14T05:56:56Z |
| format | Journal Article |
| id | curtin-20.500.11937-3152 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T05:56:56Z |
| publishDate | 2012 |
| publisher | John Wiley & Sons |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-31522017-09-13T15:54:28Z Synthesis and structure of 3,4-dihydropyrido[2’,3’:3,4]pyrazolo[1,5-a][1,3,5]triazin-2-amines Dolzhenko, Anton Bai, S. Dolzhenko, A. Chui, W. pyridines triazines guanidines tautomerism pyrazoles A new convenient synthon for heterocyclic chemistry, namely 1H-pyrazolo[3,4-b]pyridin-3-ylguanidine was successfully prepared by selective guanylation of 1H-pyrazolo[3,4-b]pyridin-3-amine. A series of 3,4-dihydropyrido[2′,3′:3,4]pyrazolo[1,5-a][1,3,5]triazin-2-amines was synthesized from 1H-pyrazolo[3,4-b]pyridin-3-ylguanidine using aldehydes or ketones as one-carbon inserting reagents. The tautomeric preferences of the products were determined using spectroscopic (e.g., 2D NOESY NMR) and single crystal X-ray diffraction data. 2012 Journal Article http://hdl.handle.net/20.500.11937/3152 10.1002/jhet.851 John Wiley & Sons restricted |
| spellingShingle | pyridines triazines guanidines tautomerism pyrazoles Dolzhenko, Anton Bai, S. Dolzhenko, A. Chui, W. Synthesis and structure of 3,4-dihydropyrido[2’,3’:3,4]pyrazolo[1,5-a][1,3,5]triazin-2-amines |
| title | Synthesis and structure of 3,4-dihydropyrido[2’,3’:3,4]pyrazolo[1,5-a][1,3,5]triazin-2-amines |
| title_full | Synthesis and structure of 3,4-dihydropyrido[2’,3’:3,4]pyrazolo[1,5-a][1,3,5]triazin-2-amines |
| title_fullStr | Synthesis and structure of 3,4-dihydropyrido[2’,3’:3,4]pyrazolo[1,5-a][1,3,5]triazin-2-amines |
| title_full_unstemmed | Synthesis and structure of 3,4-dihydropyrido[2’,3’:3,4]pyrazolo[1,5-a][1,3,5]triazin-2-amines |
| title_short | Synthesis and structure of 3,4-dihydropyrido[2’,3’:3,4]pyrazolo[1,5-a][1,3,5]triazin-2-amines |
| title_sort | synthesis and structure of 3,4-dihydropyrido[2’,3’:3,4]pyrazolo[1,5-a][1,3,5]triazin-2-amines |
| topic | pyridines triazines guanidines tautomerism pyrazoles |
| url | http://hdl.handle.net/20.500.11937/3152 |