A Clonal Complex 12 Methicillin-Resistant Staphylococcus aureus Strain, West Australian MRSA-59, Harbors a Novel Pseudo-SCCmec Element

Copyright © 2015, American Society for Microbiology. All Rights Reserved. A West Australian methicillin-resistant Staphylococcus aureus strain (WA MRSA-59) was characterized by microarray and sequencing. Its pseudo-staphylococcal cassette chromosome mec (SCCmec) element comprised dcs, Q9XB68-dcs, mv...

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Main Authors: Monecke, S., Coombs, Geoffrey, Pearson, J., Hotzel, H., Slickers, P., Ehricht, R.
Format: Journal Article
Published: 2015
Online Access:http://hdl.handle.net/20.500.11937/31513
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author Monecke, S.
Coombs, Geoffrey
Pearson, J.
Hotzel, H.
Slickers, P.
Ehricht, R.
author_facet Monecke, S.
Coombs, Geoffrey
Pearson, J.
Hotzel, H.
Slickers, P.
Ehricht, R.
author_sort Monecke, S.
building Curtin Institutional Repository
collection Online Access
description Copyright © 2015, American Society for Microbiology. All Rights Reserved. A West Australian methicillin-resistant Staphylococcus aureus strain (WA MRSA-59) was characterized by microarray and sequencing. Its pseudo-staphylococcal cassette chromosome mec (SCCmec) element comprised dcs, Q9XB68-dcs, mvaS-SCC, Q5HJW6, dru, ugpQ, ydeM, mecA-mecR-mecI, txbi mecI, tnp IS431, copA2-mco (copper resistance), ydhK, arsC-arsB-arsR (arsenic resistance), open reading frame PT43, and per-2. Recombinase genes, xylR (mecR2), and PSM-mec (phenol-soluble modulin) were absent. We suggest that mec complex A should be split into two subtypes. One harbors PSM-mec and xylR (mecR2). It is found in SCCmec types II, III, and VIII. The second subtype, described herein, is present in WA MRSA-59 and some coagulasenegative staphylococci.
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spelling curtin-20.500.11937-315132023-02-22T06:24:16Z A Clonal Complex 12 Methicillin-Resistant Staphylococcus aureus Strain, West Australian MRSA-59, Harbors a Novel Pseudo-SCCmec Element Monecke, S. Coombs, Geoffrey Pearson, J. Hotzel, H. Slickers, P. Ehricht, R. Copyright © 2015, American Society for Microbiology. All Rights Reserved. A West Australian methicillin-resistant Staphylococcus aureus strain (WA MRSA-59) was characterized by microarray and sequencing. Its pseudo-staphylococcal cassette chromosome mec (SCCmec) element comprised dcs, Q9XB68-dcs, mvaS-SCC, Q5HJW6, dru, ugpQ, ydeM, mecA-mecR-mecI, txbi mecI, tnp IS431, copA2-mco (copper resistance), ydhK, arsC-arsB-arsR (arsenic resistance), open reading frame PT43, and per-2. Recombinase genes, xylR (mecR2), and PSM-mec (phenol-soluble modulin) were absent. We suggest that mec complex A should be split into two subtypes. One harbors PSM-mec and xylR (mecR2). It is found in SCCmec types II, III, and VIII. The second subtype, described herein, is present in WA MRSA-59 and some coagulasenegative staphylococci. 2015 Journal Article http://hdl.handle.net/20.500.11937/31513 10.1128/AAC.01745-15 unknown
spellingShingle Monecke, S.
Coombs, Geoffrey
Pearson, J.
Hotzel, H.
Slickers, P.
Ehricht, R.
A Clonal Complex 12 Methicillin-Resistant Staphylococcus aureus Strain, West Australian MRSA-59, Harbors a Novel Pseudo-SCCmec Element
title A Clonal Complex 12 Methicillin-Resistant Staphylococcus aureus Strain, West Australian MRSA-59, Harbors a Novel Pseudo-SCCmec Element
title_full A Clonal Complex 12 Methicillin-Resistant Staphylococcus aureus Strain, West Australian MRSA-59, Harbors a Novel Pseudo-SCCmec Element
title_fullStr A Clonal Complex 12 Methicillin-Resistant Staphylococcus aureus Strain, West Australian MRSA-59, Harbors a Novel Pseudo-SCCmec Element
title_full_unstemmed A Clonal Complex 12 Methicillin-Resistant Staphylococcus aureus Strain, West Australian MRSA-59, Harbors a Novel Pseudo-SCCmec Element
title_short A Clonal Complex 12 Methicillin-Resistant Staphylococcus aureus Strain, West Australian MRSA-59, Harbors a Novel Pseudo-SCCmec Element
title_sort clonal complex 12 methicillin-resistant staphylococcus aureus strain, west australian mrsa-59, harbors a novel pseudo-sccmec element
url http://hdl.handle.net/20.500.11937/31513