Diagnostic value of 64-slice CT angiography in coronary artery disease: a systematic review
Purpose: To perform a systematic review of the diagnostic value of 64-multislice CT (MSCT) angiography in the detection of coronary artery disease (CAD) when compared to conventional coronary angiography. Materials and methods: A search of PUBMED and MEDLINE databases for English literature was perf...
| Main Authors: | , , , , |
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| Format: | Journal Article |
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Elsevier Ireland Ltd
2008
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| Online Access: | http://hdl.handle.net/20.500.11937/31341 |
| _version_ | 1848753352480915456 |
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| author | Sun, Zhonghua Lin, C. Davidson, R. Dong, C. Liao, Y. |
| author_facet | Sun, Zhonghua Lin, C. Davidson, R. Dong, C. Liao, Y. |
| author_sort | Sun, Zhonghua |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Purpose: To perform a systematic review of the diagnostic value of 64-multislice CT (MSCT) angiography in the detection of coronary artery disease (CAD) when compared to conventional coronary angiography. Materials and methods: A search of PUBMED and MEDLINE databases for English literature was performed. Only studies with at least 10 patients comparing 64-slice MSCT angiography with conventional coronary angiography in the detection of CAD were included. Diagnostic value of MSCT angiography compared to coronary angiography was compared and analysed at segment-, vessel- and patient-based assessment. Results: Fifteen studies met selection criteria and were included for analysis. Pooled sensitivity, specificity, positive predictive value and negative predictive value as well as 95% confidence interval (CI) were 97% (94 and 99%), 88% (79 and 97%), 94% (91 and 97%), and 95% (90 and 99%) for patient-based assessment; 92% (85 and 99%), 92% (85 and 99%), 78% (66 and 91%) and 98% (96 and 99%) for vessel-based assessment; 90% (85 and 94%), 96% (95 and 97%), 75%(68 and 82%) and 98% (98 and 99%) for segment-based assessment, respectively. No significant difference was found in the diagnostic accuracy of 64-slice CT in the detection of CAD when comparison was performed either among four main coronary arteries, or between proximal and middle or distal segments (p > 0.05). Conclusion: Our results showed that 64-slice CT angiography has a high-diagnostic value in the detection of CAD. Severe coronary artery calcification seems to be the major factor affecting the visualisation and assessment. |
| first_indexed | 2025-11-14T08:23:09Z |
| format | Journal Article |
| id | curtin-20.500.11937-31341 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:23:09Z |
| publishDate | 2008 |
| publisher | Elsevier Ireland Ltd |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-313412017-09-13T15:56:20Z Diagnostic value of 64-slice CT angiography in coronary artery disease: a systematic review Sun, Zhonghua Lin, C. Davidson, R. Dong, C. Liao, Y. Purpose: To perform a systematic review of the diagnostic value of 64-multislice CT (MSCT) angiography in the detection of coronary artery disease (CAD) when compared to conventional coronary angiography. Materials and methods: A search of PUBMED and MEDLINE databases for English literature was performed. Only studies with at least 10 patients comparing 64-slice MSCT angiography with conventional coronary angiography in the detection of CAD were included. Diagnostic value of MSCT angiography compared to coronary angiography was compared and analysed at segment-, vessel- and patient-based assessment. Results: Fifteen studies met selection criteria and were included for analysis. Pooled sensitivity, specificity, positive predictive value and negative predictive value as well as 95% confidence interval (CI) were 97% (94 and 99%), 88% (79 and 97%), 94% (91 and 97%), and 95% (90 and 99%) for patient-based assessment; 92% (85 and 99%), 92% (85 and 99%), 78% (66 and 91%) and 98% (96 and 99%) for vessel-based assessment; 90% (85 and 94%), 96% (95 and 97%), 75%(68 and 82%) and 98% (98 and 99%) for segment-based assessment, respectively. No significant difference was found in the diagnostic accuracy of 64-slice CT in the detection of CAD when comparison was performed either among four main coronary arteries, or between proximal and middle or distal segments (p > 0.05). Conclusion: Our results showed that 64-slice CT angiography has a high-diagnostic value in the detection of CAD. Severe coronary artery calcification seems to be the major factor affecting the visualisation and assessment. 2008 Journal Article http://hdl.handle.net/20.500.11937/31341 10.1016/j.ejrad.2007.07.014 Elsevier Ireland Ltd restricted |
| spellingShingle | Sun, Zhonghua Lin, C. Davidson, R. Dong, C. Liao, Y. Diagnostic value of 64-slice CT angiography in coronary artery disease: a systematic review |
| title | Diagnostic value of 64-slice CT angiography in coronary artery disease: a systematic review |
| title_full | Diagnostic value of 64-slice CT angiography in coronary artery disease: a systematic review |
| title_fullStr | Diagnostic value of 64-slice CT angiography in coronary artery disease: a systematic review |
| title_full_unstemmed | Diagnostic value of 64-slice CT angiography in coronary artery disease: a systematic review |
| title_short | Diagnostic value of 64-slice CT angiography in coronary artery disease: a systematic review |
| title_sort | diagnostic value of 64-slice ct angiography in coronary artery disease: a systematic review |
| url | http://hdl.handle.net/20.500.11937/31341 |