A conserved host and pathogen recognition site on immunoglobulins: Structural and functional aspects

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A conserved host and pathogen recognition site on immunoglobulins: Structural and functional aspects

A common site in the constant region (Fc) of immunoglobulins is recognized by host receptors and is a frequent target of proteins expressed by pathogens. This site is located at the junction of two constant domains in the antibody heavy chains and produces a large shallow cavity formed by loops of t...

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Bibliographic Details
Main Authors:	Wines, B., Trist, H., Farrugia, W., Ngo, C., Trowsdale, J., Areschoug, T., Lindahl, G., Fraser, J., Ramsland, Paul
Format:	Book Chapter
Published:	2012
Online Access:	http://hdl.handle.net/20.500.11937/3090

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