Coronary CT angiography: Beyond morphological stenosis analysis

Rapid technological developments in computed tomography (CT) imaging technique have made coronary CT angiography an attractive imaging tool in the detection of coronary artery disease. Despite visualization of excellent anatomical details of the coronary lumen changes, coronary CT angiography does n...

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Main Author: Sun, Zhonghua
Format: Journal Article
Published: Beijing Baishideng BioMed Scientific Co., Ltd 2013
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/30813
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author Sun, Zhonghua
author_facet Sun, Zhonghua
author_sort Sun, Zhonghua
building Curtin Institutional Repository
collection Online Access
description Rapid technological developments in computed tomography (CT) imaging technique have made coronary CT angiography an attractive imaging tool in the detection of coronary artery disease. Despite visualization of excellent anatomical details of the coronary lumen changes, coronary CT angiography does not provide hemodynamic changes caused by presence of plaques. Computational fluid dynamics (CFD) is a widely used method in the mechanical engineering field to solve complex problems through analysing fluid flow, heat transfer and associated phenomena by using computer simulations. In recent years, CFD is increasingly used in biomedical research due to high performance hardware and software. CFD techniques have been used to study cardiovascular hemodynamics through simulation tools to assist in predicting the behaviour of circulatory blood flow inside the human body. Blood flow plays a key role in the localization and progression of coronary artery disease. CFD simulation based on 3D luminal reconstructions can be used to analyse the local flow fields and flow profiling due to changes of vascular geometry, thus, identifying risk factors for development of coronary artery disease. The purpose of this article is to provide an overview of the coronary CT-derived CFD applications in coronary artery disease.
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spelling curtin-20.500.11937-308132017-09-13T15:09:36Z Coronary CT angiography: Beyond morphological stenosis analysis Sun, Zhonghua Coronary artery disease Computational fluid dynamics Hemodynamics Modelling Rapid technological developments in computed tomography (CT) imaging technique have made coronary CT angiography an attractive imaging tool in the detection of coronary artery disease. Despite visualization of excellent anatomical details of the coronary lumen changes, coronary CT angiography does not provide hemodynamic changes caused by presence of plaques. Computational fluid dynamics (CFD) is a widely used method in the mechanical engineering field to solve complex problems through analysing fluid flow, heat transfer and associated phenomena by using computer simulations. In recent years, CFD is increasingly used in biomedical research due to high performance hardware and software. CFD techniques have been used to study cardiovascular hemodynamics through simulation tools to assist in predicting the behaviour of circulatory blood flow inside the human body. Blood flow plays a key role in the localization and progression of coronary artery disease. CFD simulation based on 3D luminal reconstructions can be used to analyse the local flow fields and flow profiling due to changes of vascular geometry, thus, identifying risk factors for development of coronary artery disease. The purpose of this article is to provide an overview of the coronary CT-derived CFD applications in coronary artery disease. 2013 Journal Article http://hdl.handle.net/20.500.11937/30813 10.4330/wjc.v5.i12.444 Beijing Baishideng BioMed Scientific Co., Ltd fulltext
spellingShingle Coronary artery disease
Computational fluid dynamics
Hemodynamics
Modelling
Sun, Zhonghua
Coronary CT angiography: Beyond morphological stenosis analysis
title Coronary CT angiography: Beyond morphological stenosis analysis
title_full Coronary CT angiography: Beyond morphological stenosis analysis
title_fullStr Coronary CT angiography: Beyond morphological stenosis analysis
title_full_unstemmed Coronary CT angiography: Beyond morphological stenosis analysis
title_short Coronary CT angiography: Beyond morphological stenosis analysis
title_sort coronary ct angiography: beyond morphological stenosis analysis
topic Coronary artery disease
Computational fluid dynamics
Hemodynamics
Modelling
url http://hdl.handle.net/20.500.11937/30813