Altered peptide ligands of myelin basic protein (MBP87-99) conjugated to reduced mannan modulate immune responses in mice

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Altered peptide ligands of myelin basic protein (MBP87-99) conjugated to reduced mannan modulate immune responses in mice

Mutations of peptides to generate altered peptide ligands, capable of switching immune responses from T helper 1 (Th1) to T helper 2 (Th2), are promising candidates for the immunotherapy of autoimmune diseases such as multiple sclerosis (MS). We synthesized two mutant peptides from myelin basic prot...

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Bibliographic Details
Main Authors:	Katsara, M., Yuriev, E., Ramsland, Paul, Tselios, T., Deraos, G., Lourbopoulos, A., Grigoriadis, N., Matsoukas, J., Apostolopoulos, V.
Format:	Journal Article
Published:	2009
Online Access:	http://hdl.handle.net/20.500.11937/30761

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