Potent long-term cardioprotective effects of single low-dose insulin-like growth factor-1 treatment postmyocardial infarction

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Potent long-term cardioprotective effects of single low-dose insulin-like growth factor-1 treatment postmyocardial infarction

Background-Insulin-like growth factor-1 (IGF-1) is recognized as an important regulator of cardiac structure and cardiomyocyte homeostasis. The prosurvival and antiapoptotic effects of IGF-1 have been investigated in vitro and in rodent models of myocardial infarction (MI). However, the clinical app...

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Bibliographic Details
Main Authors:	O'Sullivan, J., Leblond, A., Kelly, G., Kumar, A., Metharom, Pat, Büneker, C., Alizadeh-Vikali, N., Hristova, I., Hynes, B., O'Connor, R., Caplice, N.
Format:	Journal Article
Published:	2011
Online Access:	http://hdl.handle.net/20.500.11937/30558

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