Lycopene and prostate cancer: emerging evidence

Prostate cancer has the third highest incidence of all cancers in men worldwide and is the most common neoplasm diagnosed among men beyond middle age in many developed countries. Mounting evidence surrounding the consumption of tomato products has shown promise for the prevention of prostate cancer....

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Main Authors: Fraser, Michelle, Lee, Andy, Binns, Colin
Format: Journal Article
Published: Future Drugs 2005
Online Access:http://hdl.handle.net/20.500.11937/3039
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author Fraser, Michelle
Lee, Andy
Binns, Colin
author_facet Fraser, Michelle
Lee, Andy
Binns, Colin
author_sort Fraser, Michelle
building Curtin Institutional Repository
collection Online Access
description Prostate cancer has the third highest incidence of all cancers in men worldwide and is the most common neoplasm diagnosed among men beyond middle age in many developed countries. Mounting evidence surrounding the consumption of tomato products has shown promise for the prevention of prostate cancer. This protective effect has more recently been linked to lycopene, the most abundant carotenoid in tomatoes. Lycopene is a natural pigment that gives the red color to many foods. In Western countries, 85% of dietary lycopene can be attributed to the consumption of tomato-based products. This article reviews emerging evidence from epidemiologic studies for the role of lycopene in prostate cancer prevention. The majority of evidence currently comes from observational studies, but recent human clinical trials and animal studies have provided additional support. Growing evidence on the biologic mechanisms of lycopene in prostate cancer prevention also confirm the epidemiologic findings.
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spelling curtin-20.500.11937-30392018-09-07T03:30:50Z Lycopene and prostate cancer: emerging evidence Fraser, Michelle Lee, Andy Binns, Colin Prostate cancer has the third highest incidence of all cancers in men worldwide and is the most common neoplasm diagnosed among men beyond middle age in many developed countries. Mounting evidence surrounding the consumption of tomato products has shown promise for the prevention of prostate cancer. This protective effect has more recently been linked to lycopene, the most abundant carotenoid in tomatoes. Lycopene is a natural pigment that gives the red color to many foods. In Western countries, 85% of dietary lycopene can be attributed to the consumption of tomato-based products. This article reviews emerging evidence from epidemiologic studies for the role of lycopene in prostate cancer prevention. The majority of evidence currently comes from observational studies, but recent human clinical trials and animal studies have provided additional support. Growing evidence on the biologic mechanisms of lycopene in prostate cancer prevention also confirm the epidemiologic findings. 2005 Journal Article http://hdl.handle.net/20.500.11937/3039 10.1586/14737140.5.5.847 Future Drugs restricted
spellingShingle Fraser, Michelle
Lee, Andy
Binns, Colin
Lycopene and prostate cancer: emerging evidence
title Lycopene and prostate cancer: emerging evidence
title_full Lycopene and prostate cancer: emerging evidence
title_fullStr Lycopene and prostate cancer: emerging evidence
title_full_unstemmed Lycopene and prostate cancer: emerging evidence
title_short Lycopene and prostate cancer: emerging evidence
title_sort lycopene and prostate cancer: emerging evidence
url http://hdl.handle.net/20.500.11937/3039