Physical inactivity is associated with moderate-severe obstructive sleep apnea
Study Objectives: To investigate whether low levels of physical activity were associated with an increased occurrence of obstructive sleep apnea (OSA), OSA-related symptoms, and cardiometabolic risk. Methods: A case-control study design was used. OSA cases were patients referred to a sleep clinic fo...
| Main Authors: | , , , , , , , , |
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| Format: | Journal Article |
| Published: |
2015
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| Online Access: | http://hdl.handle.net/20.500.11937/30046 |
| _version_ | 1848752975130918912 |
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| author | Simpson, L. McArdle, N. Eastwood, Peter Ward, K. Cooper, M. Wilson, A. Hillman, D. Palmer, L. Mukherjee, S. |
| author_facet | Simpson, L. McArdle, N. Eastwood, Peter Ward, K. Cooper, M. Wilson, A. Hillman, D. Palmer, L. Mukherjee, S. |
| author_sort | Simpson, L. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Study Objectives: To investigate whether low levels of physical activity were associated with an increased occurrence of obstructive sleep apnea (OSA), OSA-related symptoms, and cardiometabolic risk. Methods: A case-control study design was used. OSA cases were patients referred to a sleep clinic for suspected OSA (n = 2,340). Controls comprised participants from the Busselton community (n = 1,931). Exercise and occupational activity were derived from questionnaire data. Associations were modelled using logistic and linear regression and adjusted for confounders. Results: In comparison with moderate exercise, the high, low, and nil exercise groups had an odds ratio (OR) for moderate-severe OSA of 0.6 (95% CI 0.5-0.8), 1.6 (95% CI 1.2-2.0), and 2.7 (95% CI 1.9-3.7), respectively. Relative to men in heavy activity occupations, men in medium, light and sedentary occupations had an OR for moderate-severe OSA of 1.7 (95% CI 1.1-2.5), 2.1 (95% CI 1.4-3.2), and 1.8 (95% CI 1.2-2.8), respectively. Relative to women in medium activity occupations, women in light and sedentary occupations had an OR for moderate-severe OSA of 4.2 (95% CI 2.6-7.2) and 3.5 (2.0-6.0). OSA patients who adequately exercised had lower: levels of doctor-diagnosed depression (p = 0.047); symptoms of fatigue (p < 0.0001); systolic (p = 0.015) and diastolic blood pressure (p = 0.015); and C-reactive protein (CRP) (p = 0.003). Conclusions: Low levels of physical activity were associated with moderate-severe OSA. Exercise in individuals with OSA is associated with lower levels of depression, fatigue, blood pressure and CRP. |
| first_indexed | 2025-11-14T08:17:09Z |
| format | Journal Article |
| id | curtin-20.500.11937-30046 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:17:09Z |
| publishDate | 2015 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-300462018-03-29T09:08:49Z Physical inactivity is associated with moderate-severe obstructive sleep apnea Simpson, L. McArdle, N. Eastwood, Peter Ward, K. Cooper, M. Wilson, A. Hillman, D. Palmer, L. Mukherjee, S. Study Objectives: To investigate whether low levels of physical activity were associated with an increased occurrence of obstructive sleep apnea (OSA), OSA-related symptoms, and cardiometabolic risk. Methods: A case-control study design was used. OSA cases were patients referred to a sleep clinic for suspected OSA (n = 2,340). Controls comprised participants from the Busselton community (n = 1,931). Exercise and occupational activity were derived from questionnaire data. Associations were modelled using logistic and linear regression and adjusted for confounders. Results: In comparison with moderate exercise, the high, low, and nil exercise groups had an odds ratio (OR) for moderate-severe OSA of 0.6 (95% CI 0.5-0.8), 1.6 (95% CI 1.2-2.0), and 2.7 (95% CI 1.9-3.7), respectively. Relative to men in heavy activity occupations, men in medium, light and sedentary occupations had an OR for moderate-severe OSA of 1.7 (95% CI 1.1-2.5), 2.1 (95% CI 1.4-3.2), and 1.8 (95% CI 1.2-2.8), respectively. Relative to women in medium activity occupations, women in light and sedentary occupations had an OR for moderate-severe OSA of 4.2 (95% CI 2.6-7.2) and 3.5 (2.0-6.0). OSA patients who adequately exercised had lower: levels of doctor-diagnosed depression (p = 0.047); symptoms of fatigue (p < 0.0001); systolic (p = 0.015) and diastolic blood pressure (p = 0.015); and C-reactive protein (CRP) (p = 0.003). Conclusions: Low levels of physical activity were associated with moderate-severe OSA. Exercise in individuals with OSA is associated with lower levels of depression, fatigue, blood pressure and CRP. 2015 Journal Article http://hdl.handle.net/20.500.11937/30046 10.5664/jcsm.5078 restricted |
| spellingShingle | Simpson, L. McArdle, N. Eastwood, Peter Ward, K. Cooper, M. Wilson, A. Hillman, D. Palmer, L. Mukherjee, S. Physical inactivity is associated with moderate-severe obstructive sleep apnea |
| title | Physical inactivity is associated with moderate-severe obstructive sleep apnea |
| title_full | Physical inactivity is associated with moderate-severe obstructive sleep apnea |
| title_fullStr | Physical inactivity is associated with moderate-severe obstructive sleep apnea |
| title_full_unstemmed | Physical inactivity is associated with moderate-severe obstructive sleep apnea |
| title_short | Physical inactivity is associated with moderate-severe obstructive sleep apnea |
| title_sort | physical inactivity is associated with moderate-severe obstructive sleep apnea |
| url | http://hdl.handle.net/20.500.11937/30046 |