Mitochondria and diabetes: An intriguing pathogenetic role

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Mitochondria and diabetes: An intriguing pathogenetic role

Mitochondria play a key role in energy metabolism and ATP production in many tissues, including skeletal muscle, cardiac muscle, brain and liver. Inherent disorders of mitochondria such as mDNA deletions cause major disruption of metabolism and can result in severe disease phenotypes. However, the...

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Bibliographic Details
Main Authors:	Newsholme, Philip, Gaudel, C., Krause, M.
Other Authors:	Scatena, Roberto
Format:	Book Chapter
Published:	Springer New York LLC 2012
Subjects:	insulin resistance and diabetes muscle dysfunction in aging reactive oxygen species (ROS) mitochondrial dysfunction mitochondrial DNA
Online Access:	http://hdl.handle.net/20.500.11937/29670

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