Protein S is a cofactor for platelet and endothelial tissue factor pathway inhibitor-a but not for cell surface-associated tissue factor pathway inhibitor

OBJECTIVE - Tissue factor pathway inhibitor (TFPI) is produced in 2 isoforms: TFPIa, a soluble protein in plasma, platelets, and endothelial cells, and TFPIß, a glycosylphosphatidylinositol-anchored protein on endothelium. Protein S (PS) functions as a cofactor for TFPIa, enhancing the inhibition of...

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Bibliographic Details
Main Authors: Wood, J., Ellery, Paul, Maroney, S., Mast, A.
Format: Journal Article
Published: 2014
Online Access:http://hdl.handle.net/20.500.11937/29569

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