Protein S is a cofactor for platelet and endothelial tissue factor pathway inhibitor-a but not for cell surface-associated tissue factor pathway inhibitor
OBJECTIVE - Tissue factor pathway inhibitor (TFPI) is produced in 2 isoforms: TFPIa, a soluble protein in plasma, platelets, and endothelial cells, and TFPIß, a glycosylphosphatidylinositol-anchored protein on endothelium. Protein S (PS) functions as a cofactor for TFPIa, enhancing the inhibition of...
| Main Authors: | , , , |
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| Format: | Journal Article |
| Published: |
2014
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| Online Access: | http://hdl.handle.net/20.500.11937/29569 |