Occupational Exposure to Ionizing Radiation and Risk of Breast Cancer in Western Australia

Objective: To evaluate current breast cancer risk due to occupational exposure to ionizing radiation. Methods: We analyzed data from the Western Australian population-based Breast Cancer Employment and Environment Study. The Breast Cancer Employment and Environment Study included 1205 cases with inc...

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Main Authors: Buitenhuis, Wenny, Fritschi, Lin, Thomson, Allyson, Glass, Deborah, Heyworth, Jane, Peters, Susan
Format: Journal Article
Published: Lippincott Williams and Wilkins 2013
Online Access:http://hdl.handle.net/20.500.11937/29548
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author Buitenhuis, Wenny
Fritschi, Lin
Thomson, Allyson
Glass, Deborah
Heyworth, Jane
Peters, Susan
author_facet Buitenhuis, Wenny
Fritschi, Lin
Thomson, Allyson
Glass, Deborah
Heyworth, Jane
Peters, Susan
author_sort Buitenhuis, Wenny
building Curtin Institutional Repository
collection Online Access
description Objective: To evaluate current breast cancer risk due to occupational exposure to ionizing radiation. Methods: We analyzed data from the Western Australian population-based Breast Cancer Employment and Environment Study. The Breast Cancer Employment and Environment Study included 1205 cases with incident breast cancer during 2009–2011 and 1789 controls. Age-adjusted odds ratios (ORs) were estimated with logistic regression models.Results: There was a weak, not statistically significant association between breast cancer and occupational exposure to ionizing radiation (OR = 1.16; 95% confidence interval, 0.86 to 1.57). The risk of human epidermal growth factor receptor 2–positive breast cancer with occupational exposureto ionizing radiation in women who were premenopausal at the time of interview was higher (OR = 2.57; 95% confidence interval, 1.09 to 6.03).Conclusions: This study suggests that the risk of breast cancer is low at current levels of occupational exposure to ionizing radiation, although the risk of human epidermal growth factor receptor 2–positive cancer may be a concern.
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spelling curtin-20.500.11937-295482017-09-13T15:27:13Z Occupational Exposure to Ionizing Radiation and Risk of Breast Cancer in Western Australia Buitenhuis, Wenny Fritschi, Lin Thomson, Allyson Glass, Deborah Heyworth, Jane Peters, Susan Objective: To evaluate current breast cancer risk due to occupational exposure to ionizing radiation. Methods: We analyzed data from the Western Australian population-based Breast Cancer Employment and Environment Study. The Breast Cancer Employment and Environment Study included 1205 cases with incident breast cancer during 2009–2011 and 1789 controls. Age-adjusted odds ratios (ORs) were estimated with logistic regression models.Results: There was a weak, not statistically significant association between breast cancer and occupational exposure to ionizing radiation (OR = 1.16; 95% confidence interval, 0.86 to 1.57). The risk of human epidermal growth factor receptor 2–positive breast cancer with occupational exposureto ionizing radiation in women who were premenopausal at the time of interview was higher (OR = 2.57; 95% confidence interval, 1.09 to 6.03).Conclusions: This study suggests that the risk of breast cancer is low at current levels of occupational exposure to ionizing radiation, although the risk of human epidermal growth factor receptor 2–positive cancer may be a concern. 2013 Journal Article http://hdl.handle.net/20.500.11937/29548 10.1097/JOM.0b013e3182a7e692 Lippincott Williams and Wilkins restricted
spellingShingle Buitenhuis, Wenny
Fritschi, Lin
Thomson, Allyson
Glass, Deborah
Heyworth, Jane
Peters, Susan
Occupational Exposure to Ionizing Radiation and Risk of Breast Cancer in Western Australia
title Occupational Exposure to Ionizing Radiation and Risk of Breast Cancer in Western Australia
title_full Occupational Exposure to Ionizing Radiation and Risk of Breast Cancer in Western Australia
title_fullStr Occupational Exposure to Ionizing Radiation and Risk of Breast Cancer in Western Australia
title_full_unstemmed Occupational Exposure to Ionizing Radiation and Risk of Breast Cancer in Western Australia
title_short Occupational Exposure to Ionizing Radiation and Risk of Breast Cancer in Western Australia
title_sort occupational exposure to ionizing radiation and risk of breast cancer in western australia
url http://hdl.handle.net/20.500.11937/29548