Prediction of heparin binding sites in bone morphogenetic proteins (BMPs)
Heparin is a glycosaminoglycan known to bind bone morphogenetic proteins (BMPs) and the growth and differentiation factors (GDFs) and has strong and variable effects on BMP osteogenic activity. In this paper we report our predictions of the likely heparin binding sites for BMP-2 and 14. The N-termin...
| Main Authors: | Gandhi, Neha, Mancera, Ricardo |
|---|---|
| Format: | Journal Article |
| Published: |
Elsevier
2012
|
| Online Access: | http://hdl.handle.net/20.500.11937/29411 |
Similar Items
The role of bone morphogenetic proteins (BMPs) in ovarian function
by: Al-Samerria, Sarmed
Published: (2016)
by: Al-Samerria, Sarmed
Published: (2016)
Heparin/heparan sulphate-based drugs
by: Gandhi, Neha, et al.
Published: (2010)
by: Gandhi, Neha, et al.
Published: (2010)
Attenuation of Bone Morphogenetic Proteins (BMPs) Signaling Induces Granulosa Cell Sensitivity to Gonadotropins in Female Mouse
by: Al Sameira, Sarmed, et al.
Published: (2022)
by: Al Sameira, Sarmed, et al.
Published: (2022)
Computational analyses of the catalytic and heparin binding sites and their interactions with glycosaminoglycans in glycoside hydrolase family 79 endo-β-D-glucuronidase (heparanase)
by: Gandhi, Neha, et al.
Published: (2012)
by: Gandhi, Neha, et al.
Published: (2012)
Molecular dynamics simulations of CXCL-8 and its interactions with a receptor peptide, heparin fragments and sulfated cyclitols.
by: Gandhi, Neha, et al.
Published: (2011)
by: Gandhi, Neha, et al.
Published: (2011)
Influence of Heparin and Seminal Heparin Binding Proteins on Reproductive Performance of Sahiwalfriesian Bulls and Rabbits
by: Patchaiappan, Ramakrishnan
Published: (2003)
by: Patchaiappan, Ramakrishnan
Published: (2003)
Bone morphogenetic protein-2 and bone therapy: Successes and pitfalls
by: Poon, B., et al.
Published: (2016)
by: Poon, B., et al.
Published: (2016)
The Structure of Glycosaminoglycans and their Interactions with Proteins
by: Gandhi, Neha, et al.
Published: (2008)
by: Gandhi, Neha, et al.
Published: (2008)
Free energy calculations of glycosaminoglycan-protein interactions
by: Gandhi, Neha, et al.
Published: (2009)
by: Gandhi, Neha, et al.
Published: (2009)
Involvement of Bone Morphogenetic Proteins (BMP) in the Regulation of Ovarian Function
by: Regan, S., et al.
Published: (2018)
by: Regan, S., et al.
Published: (2018)
Computational Methods for the Prediction of the Structure and Interactions of Coiled-Coil Peptides
by: Gandhi, Neha, et al.
Published: (2008)
by: Gandhi, Neha, et al.
Published: (2008)
The mode of action of bone morphogenetic protein (bmp) in the regulation of ovarian function
by: Regan, Sheena Linnette Patricia
Published: (2015)
by: Regan, Sheena Linnette Patricia
Published: (2015)
Molecular dynamics simulations of ligand-induced backbone conformational changes in the binding site of the periplasmic lysine-, arginine-, ornithine-binding protein
by: Yang, A., et al.
Published: (2008)
by: Yang, A., et al.
Published: (2008)
A New Method for Estimating the Importance of Hydrophobic Groups in the Binding Site of a Protein
by: Kelly, M., et al.
Published: (2005)
by: Kelly, M., et al.
Published: (2005)
Development and application of site mapping methods for the design of glycosaminoglycans
by: Agostino, Mark, et al.
Published: (2014)
by: Agostino, Mark, et al.
Published: (2014)
Understanding insulin endocrinology in decapod crustacea: Molecular modelling characterization of an insulin-binding protein and insulin-like peptides in the eastern spiny lobster, Sagmariasus verreauxi
by: Chandler, J., et al.
Published: (2017)
by: Chandler, J., et al.
Published: (2017)
Ovarian follicle development in Booroola sheep exhibiting impaired bone morphogenetic protein signalling pathway
by: Ruoss, Chantelle, et al.
Published: (2009)
by: Ruoss, Chantelle, et al.
Published: (2009)
Detection of bone morphogenetic protein 2 within avian genome using PCR-based method
by: Teh, Richard, et al.
Published: (2013)
by: Teh, Richard, et al.
Published: (2013)
mRNA Expression Of Bone
Morphogenetic Protein 7 (bmp7) During
Folliculogenesis In Zebrafish
by: Lim, Phaik Siew
Published: (2011)
by: Lim, Phaik Siew
Published: (2011)
Developing drugs from sugars: current state of glycosaminoglycan-derived therapeutics
by: Gandhi, Neha, et al.
Published: (2012)
by: Gandhi, Neha, et al.
Published: (2012)
Can current force fields reproduce ring puckering in 2-O-sulfo-?-L-iduronic acid? A molecular dynamics simulation study
by: Gandhi, Neha, et al.
Published: (2010)
by: Gandhi, Neha, et al.
Published: (2010)
A biodegradable system for the tailored delivery of growth factors and its application to bone morphogenetic protein-2 delivery for bone repair
by: Cox, Helen Celia
Published: (2013)
by: Cox, Helen Celia
Published: (2013)
Free Energy Calculations of the Interactions of c-Jun-based Synthetic Peptides with the c-Fos Protein
by: Zuo, Zhili, et al.
Published: (2012)
by: Zuo, Zhili, et al.
Published: (2012)
Comparative analysis of the surface interaction properties of the binding sites of CDK2, CDK4 and ERK2
by: Kelly, M., et al.
Published: (2006)
by: Kelly, M., et al.
Published: (2006)
Heparin mimetics
by: Coombe, Deidre, et al.
Published: (2012)
by: Coombe, Deidre, et al.
Published: (2012)
Functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production
by: Glister, Claire, et al.
Published: (2013)
by: Glister, Claire, et al.
Published: (2013)
Docking of carbohydrates into protein binding sites
by: Agostino, Mark, et al.
Published: (2012)
by: Agostino, Mark, et al.
Published: (2012)
Atomistic molecular dynamics simulations of bioactive engrailed 1 interference peptides (EN1-iPeps)
by: Gandhi, Neha, et al.
Published: (2018)
by: Gandhi, Neha, et al.
Published: (2018)
Molecular dynamics simulation of the phosphorylation-induced conformational changes of a tau peptide fragment
by: Lyons, Albert, et al.
Published: (2014)
by: Lyons, Albert, et al.
Published: (2014)
Calculations of the free energy of interaction of the cFos-cJun coiled coil: effects of the solvation model and the inclusion of polarization effects
by: Zuo, Zhili, et al.
Published: (2010)
by: Zuo, Zhili, et al.
Published: (2010)
Platelet endothelial cell adhesion molecule (PECAM-1) and its interactions with glycosaminoglycans 1. Molecular modelling studies
by: Gandhi, Neha, et al.
Published: (2008)
by: Gandhi, Neha, et al.
Published: (2008)
LTBP-2 competes with tropoelastin for binding to fibulin-5 and heparin, and is a negative modulator of elastinogenesis
by: Mohamed Sideek, Mohamed Arshad, et al.
Published: (2013)
by: Mohamed Sideek, Mohamed Arshad, et al.
Published: (2013)
Relationship between bull fertility and binding of 3H heparin to spermatozoa in Sahiwal-Friesian bull
by: Patchaiappan, Ramakrishnan, et al.
Published: (2006)
by: Patchaiappan, Ramakrishnan, et al.
Published: (2006)
Computational site-directed mutagenesis studies of the role of the hydrophobic triad on substrate binding in cholesterol oxidase
by: Harb, L., et al.
Published: (2017)
by: Harb, L., et al.
Published: (2017)
Dysregulation of granulosal bone morphogenetic protein receptor 1B density is associated with reduced ovarian reserve and the age-related decline in human fertility
by: Regan, S., et al.
Published: (2016)
by: Regan, S., et al.
Published: (2016)
The evaluation of cartilage differentiations using transforming growth factor beta3 alone and with combination of bone morphogenetic protein-6 on adult stem cells
by: Ude, C. C., et al.
Published: (2017)
by: Ude, C. C., et al.
Published: (2017)
Heparin for assisted reproduction (Review)
by: Akhtar, Muhammad A., et al.
Published: (2013)
by: Akhtar, Muhammad A., et al.
Published: (2013)
Heparin mimetics: Their therapeutic potential
by: Mohamed, Shifaza, et al.
Published: (2017)
by: Mohamed, Shifaza, et al.
Published: (2017)
Molecular modelling of the interactions of complex carbohydrates with proteins
by: Gandhi, Neha Sureshchandra
Published: (2011)
by: Gandhi, Neha Sureshchandra
Published: (2011)
The molecular binding interactions of inhibitors and activators of phosphoenolpyruvate carboxylase
by: Mancera, Ricardo, et al.
Published: (2005)
by: Mancera, Ricardo, et al.
Published: (2005)
Similar Items
-
The role of bone morphogenetic proteins (BMPs) in ovarian function
by: Al-Samerria, Sarmed
Published: (2016) -
Heparin/heparan sulphate-based drugs
by: Gandhi, Neha, et al.
Published: (2010) -
Attenuation of Bone Morphogenetic Proteins (BMPs) Signaling Induces Granulosa Cell Sensitivity to Gonadotropins in Female Mouse
by: Al Sameira, Sarmed, et al.
Published: (2022) -
Computational analyses of the catalytic and heparin binding sites and their interactions with glycosaminoglycans in glycoside hydrolase family 79 endo-β-D-glucuronidase (heparanase)
by: Gandhi, Neha, et al.
Published: (2012) -
Molecular dynamics simulations of CXCL-8 and its interactions with a receptor peptide, heparin fragments and sulfated cyclitols.
by: Gandhi, Neha, et al.
Published: (2011)